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Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.

The study found that p63 needs signals from morphogens to help skin cells differentiate properly.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Benign skin tumors need accurate diagnosis to ensure proper treatment.

Hair and nail conditions can stabilize or improve over time, and new treatments show promise.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.