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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Hesperidin from orange peels is a promising natural ingredient for skincare due to its multiple beneficial properties.

Skin has specialized touch receptors that can tell different sensations apart.

c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.

Plant-based products can improve hair and skin health without harmful side effects.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.

Finasteride may cause kidney damage.

Plasma-activated liquid can kill harmful cells, speed up wound healing, and potentially treat cancer without damaging healthy cells.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

Onions may help reduce cancer risk and obesity-related issues.

Platelet-Rich Plasma therapy significantly increases hair density in people with Androgenic Alopecia, and works better with more treatments per month and in younger patients.

The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.