6 citations
,
April 2012 in “PloS one” This study used transgenic mice to show that disrupting TGF-β signaling in K14+ progenitor cells led to increased stem cell proliferation in the tongue.
1 citations
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April 2023 in “International journal of molecular sciences” In this study, AMACO was found to be non-essential for the formation or function of anchoring cords in mice, despite its presence in the structure.
March 2021 in “Der Hautarzt” This review covers the clinical features, pathophysiology, differential diagnoses, and therapeutic options for neuroendocrine paraneoplastic syndromes affecting the skin but reports no new clinical findings.
2 citations
,
September 2011 in “Der Urologe” This review discusses the role of vitamins, micronutrients, and diets in prostate cancer prevention and reports no new clinical results, emphasizing a shift towards focusing on diet over supplements.
46 citations
,
May 2003 in “Mechanisms of Development” This study found that overexpression of the calcium sensing receptor in transgenic mice accelerates epidermal differentiation and hair growth, suggesting its role in enhancing calcium signaling and interaction with other pathways.
17 citations
,
July 2024 in “Frontiers in Oncology” This review discusses recent advances in understanding Merkel cell carcinoma biology, including the development of genetically-engineered mouse models and potential therapeutic targets, but reports no new clinical results.
13 citations
,
January 2023 in “Annual Review of Cancer Biology” This study suggests that cancer risk may be influenced by the balance of pro- and anti-oncogenic mutants in normal tissues rather than by the total number of mutations.
13 citations
,
March 2017 in “PubMed” In this study, patients with androgenetic alopecia showed significantly decreased antioxidant activity and increased oxidative stress markers, suggesting a role for oxidative stress in the condition.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” This study revealed that deleting EZH2 in mesenchyme-derived cells of the female reproductive tract led to impaired uterine gland development and pregnancy loss in mice, highlighting EZH2's crucial role in fertility.
5 citations
,
May 2023 in “Frontiers in Immunology” This review provides an overview of how advancing imaging technologies, such as tissue clearing and intravital microscopy, are enhancing our understanding of tumor architecture and interactions between cancer cells and the tumor microenvironment, aiding both fundamental cancer research and the development of therapies.
2 citations
,
April 2024 in “Anais Brasileiros de Dermatologia” Pre-existing skin conditions and drug reactions are the main causes of exfoliative erythroderma.
2 citations
,
March 2022 in “Journal of Personalized Medicine” Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.
August 2025 in “American Journal of Dermatopathology” In this study, researchers presented cases of cellular neurothekeoma in three male family members with early-onset in infancy, suggesting a potential genetic component and inheritance pattern, which deviates from the typical presentation seen mostly in women between 20–30 years.
May 2025 in “International Journal of Cosmetic Science” In this study, researchers found that a shampoo containing caffeine and adenosine significantly altered the scalp microbiome and lipidome in subjects with hair loss over 12 weeks, which may suggest a role for these compounds in enhancing anti-hair loss processes.
December 2024 in “Cureus” This study observed that among breast cancer patients at Jinnah Hospital, Lahore, common chemotherapy side effects impacted dietary patterns, leading many patients to be moderately malnourished, while 82% were overweight or obese, posing a higher risk of cancer recurrence.
August 2023 in “Dermatology and Therapy” This review discusses the increasing reports of rare cutaneous side effects from topical imiquimod, aiming to inform physicians and dermatologists about its potential adverse effects as its use expands.
January 2019 in “Annals of Dermatology” This study observed that in Korean HIV patients, tinea infection, folliculitis, and seborrheic dermatitis were the most common skin diseases, with HAART medications generally reducing folliculitis incidence. Skin disease prevalence differed by immune status, affecting treatment needs.
October 2022 in “Biomedicines” In this rat study, offspring from females fertilized by finasteride-treated males showed hyperglycemia and increased hepatic glycogen, linking paternal androgen imbalance to liver issues across generations.
6 citations
,
June 2022 in “Dermatologic Therapy” This review discusses the biological effects of honokiol for treating skin diseases and reports no new clinical results; the authors recommend further exploration of topical applications.
409 citations
,
May 1991 in “Genes & Development” This study observed that overexpression of TGF-alpha in transgenic mice led to thicker epidermis and stunted hair growth, particularly in regions with normally thick skin and low hair density.
90 citations
,
December 2007 in “Current Oncology” This review discusses management strategies for sexual side effects of aromatase inhibitors in postmenopausal breast cancer patients and reports no original clinical findings.
72 citations
,
July 2022 in “Frontiers in Systems Biology” This review provides a comprehensive guide to the human microbiome and reports no new experimental results; it highlights the impact of modern lifestyles on microbial homeostasis and the necessity of conservation efforts.
7 citations
,
June 2024 in “iScience” This review highlights the significant role of androgens in the development and progression of cervical cancer, emphasizing the need for further research to understand their impact on the disease and improve prevention and treatment strategies in regions with limited HPV screening.
7 citations
,
February 2022 in “Journal of Personalized Medicine” This meta-analysis found that platelet-rich plasma treatments significantly increased hair density in patients with androgenic alopecia, with results influenced by treatment frequency and patient age.
4 citations
,
June 2023 in “Frontiers in Aging” This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.
1 citations
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December 2022 in “Archives of Dermatological Research” In this study, isotretinoin treatment significantly increased p53 expression in the skin of acne vulgaris patients, correlating with reduced acne severity and suggesting mechanisms for sebum suppression and side effects.
February 2025 in “International Journal of Molecular Sciences” In this study, researchers identified significant differences in lipid composition between grey and black hair follicles in women with type 2 diabetes and healthy controls, suggesting these lipids may contribute to the production of grey hair and may offer targets for anti-grey-hair treatments.
May 2023 in “Frontiers in Endocrinology” This review article discusses recent updates on the skin manifestations associated with thyroid disease, emphasizing their role as early indicators of thyroid hormone dysregulation.
February 2023 in “Frontiers in Bioengineering and Biotechnology” This review discusses the potential of optical techniques for diagnosing and treating oxidative stress-related hepatic ischemia-reperfusion injury, highlighting the need for non-invasive diagnostic methods and the anti-oxidative potential of optical therapies; it reports no new clinical results.
December 2022 in “BMC women's health” In this pilot study, the CNC® device improved body image perceptions in patients with chemotherapy-induced alopecia but did not significantly affect psychological wellbeing; it may help prevent discomfort and enhance everyday life compared to traditional wigs.