4 citations
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July 2019 in “Clinical and experimental dermatology” This abstract does not provide specific study results or findings, but it notes that the publisher is not responsible for the supplemental content's accuracy and functionality, directing any queries to the article's corresponding author.
May 2025 in “Neuropharmacology” This study in neonatal rats found that inhibiting neurosteroid synthesis with finasteride unexpectedly reduced the severity and duration of neonatal seizures following birth asphyxia, maintained cognitive functions, but increased anxiety-like behaviors, highlighting a complex role of neurosteroids in hypoxic-ischemic encephalopathy outcomes.
27 citations
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May 2008 in “Neuroscience” This study found that altering neonatal neurosteroid levels affected anxiety and aversive learning in adult rats, possibly through changes in hippocampal GABAergic functions.
17 citations
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September 2013 in “The International Journal of Neuropsychopharmacology” This study found that neonatal finasteride treatment in male rats altered hippocampal GABAA receptor subunit expression and led to increased anxiety-like behavior in response to progesterone in adulthood.
8 citations
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February 2003 in “Annals of Neurology” Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
15 citations
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April 2007 in “Journal of child neurology” This case report describes an 11-month-old boy with Menkes disease, highlighting symptoms such as developmental delays and poor therapeutic response due to significant brain and vascular abnormalities.
June 1987 in “Pediatric Neurology Briefs” This report describes a case of a 5-year-old boy with acute somnolence, alopecia, keratoconjunctivitis, and perioral stomatitis linked to lactic acidaemia.
184 citations
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August 1983 in “The journal of pediatrics/The Journal of pediatrics” In this study, biotinidase deficiency in children usually presented with neurological or skin symptoms, while metabolic ketoacidosis and organic aciduria appeared later.
157 citations
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May 2021 in “Endocrine Reviews” This review discusses recent advancements in understanding and managing congenital adrenal hyperplasia, including improvements in screening, diagnostics, and potential genetic and cell-based treatments, but reports no new clinical findings.
1 citations
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June 2010 in “Expert Review of Dermatology” Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.
18 citations
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April 2011 in “Neuropharmacology” This study found that metyrapone and etomidate provide dose-dependent anticonvulsant effects against seizures, with delayed effectiveness linked to increased neurosteroid levels.
7 citations
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May 2017 in “Behavioural brain research” This study found that manipulating neuroactive steroids during early development stages in male rats influences alcohol-induced locomotor sensitivity, suggesting their role in addiction vulnerability.
This study found that neonatal administration of finasteride reduced sensitivity to alcohol's motor-stimulating effects and increased preference for novelty and initial alcohol consumption in rats, suggesting a role in alcohol vulnerability.
724 citations
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April 2004 in “Lancet Oncology” This review summarizes the use and neonatal outcomes of chemotherapy during pregnancy, noting its potential for safe use in the second and third trimesters, and reports no new clinical results.
23 citations
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July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
January 2009 in “Side effects of drugs annual” This study observed no teratogenic effects of oral decongestants and surprisingly favorable neonatal outcomes in Swedish women who used them during pregnancy.
30 citations
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February 2003 in “Annals of Neurology” This editorial discusses the hormonal basis of catamenial epilepsy, particularly focusing on the roles of progesterone and neurosteroids, and presents no new research findings.
2 citations
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February 2003 in “Annals of Neurology” This editorial discusses the implications of neuroimaging for the treatment of epilepsy and reports no new clinical results; the author emphasizes its potential impact on therapeutic strategies.
13 citations
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September 2011 in “Archives of dermatology” This case report describes a 3-year-old male with X-linked ichthyosis and associated neurologic abnormalities, identifying an unusual cortical development malformation and suggesting that abnormal hair banding may assist diagnosis.
4 citations
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January 1970 in “Journal of Bangladesh College of Physicians and Surgeons” This report highlights a case of adrenoleukodystrophy, a rare disease, diagnosed in a young boy with neuropsychiatric symptoms and Addison's disease, stressing the importance of early diagnosis and genetic counseling.
1 citations
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February 1999 in “Journal of Paediatrics and Child Health” This book review, published in the Journal of Paediatrics and Child Health, provides no new research findings.
80 citations
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March 2004 in “Neuropediatrics” This article presents an update on a family with Coats' plus disorder, documenting additional symptoms and two new similar cases, and reviews literature suggesting a link to dyskeratosis congenita for potential molecular insights.
34 citations
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April 1973 in “The American journal of clinical nutrition” This study found that inadequate maternal pyridoxine during pregnancy led to lower body weight, slow physical development, and impaired neuromotor development in rat pups, with the severity increasing as pyridoxine levels decreased.
15 citations
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September 2018 in “Medicine” This review discusses the causes and clinical presentations of ptosis in childhood and reports on several observed cases, but provides no new clinical results.
November 2025 in “Journal of Saidu Medical College Swat” In this case report, a 2.5-year-old boy with biotinidase deficiency, initially misdiagnosed due to overlapping symptoms, showed dramatic improvement in several clinical areas after starting biotin supplementation, but persistent sensorineural hearing loss underscored the importance of early diagnosis for preventing irreversible complications.
January 2024 in “Wiadomości Lekarskie” This review addresses the historical and cultural perceptions of epilepsy and stresses the importance of understanding its diagnosis and management to lessen its psychological and social impacts, especially given the stigma often associated with this condition.
August 2018 in “Journal of The American Academy of Dermatology” Older men's scalp damage increases with age and sun exposure, a baby girl in the Philippines has Schimmelpenning syndrome, and thyroid screening is advised for children with hair loss and certain risk factors.
January 2025 in “Cermin Dunia Kedokteran” This study highlights concerns about the effects of anti-epileptic medications on pregnancy and fetal development, emphasizing the need for careful selection of these drugs for women of childbearing age with epilepsy in Indonesia.
July 2023 in “Developmental medicine and child neurology/Developmental medicine & child neurology” This study found that patients with Bachmann-Bupp syndrome treated with DFMO showed improvements in hair growth, muscle tone, and development.
166 citations
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November 2008 in “Expert Review of Endocrinology & Metabolism” This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.