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![Structure and Development of the Skin and Cutaneous Appendages](/images/research/d62f624f-b54c-4a84-8ea1-143d72bf49dd/small/35626.jpg)
research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
![Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis](/images/research/b7f1dd71-5c34-438f-a61e-5e68de6fd5a7/small/12750.jpg)
research Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis
Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.
![Acrodermatitis Dysmetabolica Secondary to Isoleucine Deficiency in Infant With Maple Syrup Urine Disease](/images/research/7340aa17-e6ab-4b0a-a827-5d57b6fe1cea/small/27175.jpg)
research Acrodermatitis Dysmetabolica Secondary to Isoleucine Deficiency in Infant With Maple Syrup Urine Disease
A baby with maple syrup urine disease improved from skin problems by adjusting his diet to correct amino acid levels.
![Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome in a Saudi Child: A Case Report](/images/research/f0e28077-3a57-48fd-85a4-cc510a54cd2d/small/38211.jpg)
research Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome in a Saudi Child: A Case Report
An 8-year-old Saudi boy was diagnosed with a rare genetic disorder causing hair loss, skin issues, and light sensitivity.
![Vitamin B12 Levels in Patients with Chronic Telogen Effluvium](/images/research/875acb28-f008-46bc-a842-b86bc212871f/small/13373.jpg)
research Vitamin B12 Levels in Patients with Chronic Telogen Effluvium
People with chronic hair loss may have a higher chance of Vitamin B12 deficiency.
![Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1](/images/research/7de5a316-1f7f-480b-9a73-a6046fe860ca/small/29670.jpg)
research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1
IGF-1 increases whisker growth in transgenic mice.
![Dysregulation of the Immune System in a Natural History Study of 1299 Individuals with Down Syndrome](/images/research/bf45d485-d521-46f1-a285-c06f282d3894/small/36686.jpg)
research Dysregulation of the Immune System in a Natural History Study of 1299 Individuals with Down Syndrome
People with Down syndrome have higher rates of certain immune-related conditions and need special medical attention.
![Type II Vitamin D Dependent Rickets: A Case Report](/images/research/a60b84cc-351e-4924-8a5e-f32ad94c2e6e/small/30982.jpg)
research Type II Vitamin D Dependent Rickets: A Case Report
Hair loss can be a key sign of a rare type of rickets when vitamin D treatment doesn't work and advanced tests aren't available.
research Author Response: Type XVII Collagen Coordinates Proliferation in the Interfollicular Epidermis
Type XVII collagen helps control skin cell growth and may have anti-aging effects.
research Iron Deficiency in Menstruating Adult Women: Much More Than Anemia
Iron deficiency in menstruating women causes many health issues beyond anemia and needs early detection and treatment.
![Pseudo Pemphigus Phenotypes in Mice with Inactivated Desmoglein 3](/images/research/d51fa72f-3a7e-4e72-ae4d-41aa222ae61a/small/29162.jpg)
research Pseudo Pemphigus Phenotypes in Mice with Inactivated Desmoglein 3
Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.
![Comparing the Risk of Adverse Pregnancy Outcomes of Chinese Patients with Polycystic Ovary Syndrome with and without Antiandrogenic Pretreatment](/images/research/20d217c9-b176-4eba-98ee-ab20d79380c8/small/13713.jpg)
research Comparing the Risk of Adverse Pregnancy Outcomes of Chinese Patients with Polycystic Ovary Syndrome with and without Antiandrogenic Pretreatment
Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.
![Hair Follicle Culture: A Historical Perspective](/images/research/b2338d94-b010-4902-b348-3bf911082338/small/32389.jpg)
research Hair Follicle Culture: A Historical Perspective
Advancements in hair follicle culture have led to better understanding and potential treatments for hair loss.
![Hair Follicle Culture](/images/research/5df49f8a-9164-4fe4-948b-8280016ba610/small/29276.jpg)
research Hair Follicle Culture
Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.
![Challenges in the Diagnosis of Simple-Virilizing Congenital Adrenal Hyperplasia: A Case Report](/images/research/5df0ee7d-d7e7-436b-a8aa-9dd29c45b955/small/32698.jpg)
research Challenges in the Diagnosis of Simple-Virilizing Congenital Adrenal Hyperplasia: A Case Report
Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.
![Prevalence Of Polycystic Ovary Syndrome Among Fertile And Infertile Women In Minia Governorate, Egypt](/images/research/e42d5674-a8e3-4b0a-b3ff-3c3007b1e90a/small/14493.jpg)
research Prevalence Of Polycystic Ovary Syndrome Among Fertile And Infertile Women In Minia Governorate, Egypt
Polycystic ovary syndrome (PCOS) is a major health issue for women in Egypt, affecting 14% of fertile women and 37.5% of infertile women.
![Unusual Presentation of Denys-Drash Syndrome in a Girl with Undisclosed Consumption of Biotin](/images/research/a3c8f08b-0337-46ad-9c70-94522733eb53/small/33267.jpg)
research Unusual Presentation of Denys-Drash Syndrome in a Girl with Undisclosed Consumption of Biotin
A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
![Endocrine Abnormalities in Ring Chromosome 11: A Case Report and Review of the Literature](/images/research/14e792a0-5a68-43db-b858-00b167df4c67/small/14289.jpg)
research Endocrine Abnormalities in Ring Chromosome 11: A Case Report and Review of the Literature
Ring Chromosome 11 may be linked to conditions like early puberty, excessive hair growth, hair loss, and type 2 diabetes.
research Lasers for Dermatology and Skin Biology
Lasers have become precise tools in skin treatment and diagnosis, with ongoing advancements improving their effectiveness.
![Establishment of Keratinocyte Cell Lines from Human Hair Follicles](/images/research/51100d4f-4d9a-466e-a299-f75f70dcc385/small/35236.jpg)
research Establishment of Keratinocyte Cell Lines from Human Hair Follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
![Uncombable Hair Syndrome Due to Maternal Uniparental Disomy of Chromosome 1](/images/research/581ec38c-0c9b-426e-a6dc-1958aca7e52e/small/35178.jpg)
research Uncombable Hair Syndrome Due to Maternal Uniparental Disomy of Chromosome 1
A person got uncombable hair syndrome from two copies of chromosome 1 from their mother.
![Highlights from the 68th Annual Meeting of the Society of Investigative Dermatology](/images/research/34b2705a-fff7-40b1-9209-f7afe3c3dfd2/small/12875.jpg)
research Highlights from the 68th Annual Meeting of the Society of Investigative Dermatology
The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.
![Molecular Basis of Hair Follicle Donor Dominance in Androgenetic Alopecia and Sexual Dimorphism of the Skin](/images/research/b55eed09-0bd5-4505-8dc2-7125adeaeeee/small/4027.jpg)
research Molecular Basis of Hair Follicle Donor Dominance in Androgenetic Alopecia and Sexual Dimorphism of the Skin
Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
![Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer](/images/research/93d68c74-cccf-4f32-b557-7971747b5382/small/22095.jpg)
research Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer
Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.
![Management of Acne](/images/research/52f2d5bf-8072-4050-875f-88c42e960a9e/small/14729.jpg)
research Management of Acne
Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
![Phenotypic Profiling of Parents With Cryptic Nonclassic Congenital Adrenal Hyperplasia: Findings in 145 Unrelated Families](/images/research/a749eae1-b88b-4eab-9773-163e3961772f/small/14787.jpg)
research Phenotypic Profiling of Parents With Cryptic Nonclassic Congenital Adrenal Hyperplasia: Findings in 145 Unrelated Families
Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.
![Platelet-Rich Plasma and Hair Regeneration](/images/research/4580e0b8-064f-4a55-b87f-76ba5c17c8e9/small/23384.jpg)
research Platelet-Rich Plasma and Hair Regeneration
Platelet-rich plasma therapy might help treat some kinds of hair loss.
![Reflectance Confocal Microscopy Can Differentiate Dermoscopic White Dots of the Scalp Between Sweat Gland Ducts or Follicular Infundibulum](/images/research/f153e964-af56-4361-ac11-7bb755439dcb/small/26175.jpg)
research Reflectance Confocal Microscopy Can Differentiate Dermoscopic White Dots of the Scalp Between Sweat Gland Ducts or Follicular Infundibulum
Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.
![TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells](/images/research/80f54366-9aba-410f-9fe4-4bc33d80c318/small/37275.jpg)
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.