109 citations,
December 1998 in “The Journal of Dermatology” Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
100 citations,
November 1996 in “Molecular Medicine Today” Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
98 citations,
December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
71 citations,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
44 citations,
January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
22 citations,
August 1999 in “Experimental Dermatology” Certain drugs can cause early hair growth in mice by affecting the nerves.
8 citations,
May 2017 in “IUBMB life” Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.
5 citations,
October 2015 in “The American journal of pathology” Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.
3 citations,
January 2024 in “Signal transduction and targeted therapy” Lymphatic vessels are essential for health and can be targeted to treat various diseases.
1 citations,
July 2013 in “Hair transplant forum international” Advancements in hair follicle culture have led to better understanding and potential treatments for hair loss.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.
November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
January 2012 in “Methods in pharmacology and toxicology” Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.
271 citations,
September 2008 in “Nutrition reviews” Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
168 citations,
August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
134 citations,
December 2018 in “Dermatology and Therapy” Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
119 citations,
June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
103 citations,
December 2011 in “Journal of the American Academy of Dermatology” Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.
101 citations,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
97 citations,
April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
97 citations,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
68 citations,
March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
60 citations,
August 2008 in “Human molecular genetics online/Human molecular genetics” A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
59 citations,
October 2012 in “Pharmaceutical Research” Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.
59 citations,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
53 citations,
May 1990 in “Journal of Dermatology” Minoxidil speeds up hair growth in rats without prolonging growth phase.
47 citations,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
46 citations,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
41 citations,
May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.