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The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Keratinocytes control how melanocytes work.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Keratins are important for skin cell health and their problems can cause diseases.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

DHT, a testosterone byproduct, causes male pattern baldness.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

K16 can partially replace K14 but causes hair loss and skin issues.

Minoxidil speeds up hair growth in rats without prolonging growth phase.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Certain drugs that block specific enzymes can help treat prostate diseases.

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.