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The human skin's outer layer has more variety in cell types and development paths than previously thought.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Targeting TGFβ can improve skin immunity in older people.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Urokinase, a type of protein, helps skin cells multiply faster, especially in newborn mice.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

FoxN1 overexpression in young mice harms immune cell and skin development.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

Activin B helps start and grow hair follicles in mice.

Multi-peptide factors from fibroblasts may stimulate hair growth by increasing growth factors and β-catenin in hair cells.

The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.

The method can test hair growth products using a lab-made hair-like structure that responds to known treatments.

Early NAS level changes affect alcohol consumption vulnerability.

Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Cyclosporin A promotes hair cell growth and affects protein kinase C levels.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

A child with skin and heart issues had rare genetic mutations affecting skin and heart cell cohesion.

Norepinephrine helps skin cells grow, which is important for hair growth.

A 21-day-old baby had a skin rash that didn't improve with cream and wasn't caused by a fungus.

Certain genes controlled by OVOL1 are crucial for creating new hair follicles.