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Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.

Endocrine therapies for cancer significantly increase the risk of hair loss.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Androgens prevent hair growth by changing Wnt signals in cells.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Assessing newborn scalp hair can reveal important health information.

ECM molecules are crucial for hair growth and development.

Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.

Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

FA2H is essential for normal fur and sebum production in mice.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

CD98hc's role in skin health decreases with age.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.