79 citations
,
January 2015 in “Journal of Materials Chemistry B” This review discusses the development and future prospects of biomaterials for in situ tissue regeneration but reports no new research results; it underscores the importance of biomaterials in addressing tissue defects.
62 citations
,
October 2010 in “Journal of biomedical nanotechnology” This review discusses the challenges and contradictions in understanding nanoparticle penetration and toxicity in human skin, emphasizing the need for standardized testing and further research on particles smaller than 10 nm.
39 citations
,
February 2024 in “Small” This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.
24 citations
,
February 2021 in “Polymers” This study found that urchin-like Ag–Au bimetallic and Ag nanoparticle-decorated PAN mats showed significant antibacterial effects and potential for wound healing in in vitro and in vivo animal models.
14 citations
,
December 2024 in “Pharmaceutics” This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.
30 citations
,
November 2024 in “ACS Materials Au” This article provides an overview of microneedle technology for transcutaneous drug delivery, discussing microneedle designs, materials, and activation methods that enhance drug stability and regulated release, and outlines considerations for their successful clinical implementation, such as biocompatibility and production cost.
4 citations
,
July 2021 in “Journal of dermatology & dermatologic surgery” This review discusses the use of microneedling with a dermaroller for treating acne scars, hair loss, and wrinkles, and reports no new clinical results.
July 2025 in “Nano Research” This review highlights the application of microneedle technology as a promising advancement in psoriasis management, focusing on its roles in enhanced transdermal drug delivery and minimally invasive biomarker monitoring, while also discussing current challenges and future research directions.
July 2026 in “Pharmaceuticals” This review discusses the potential of marine-derived polysaccharide nanofibers as advanced wound dressings, highlighting their regenerative advantages in addressing inflammation, oxidative stress, and other healing barriers. However, it notes that clinical translation is limited by challenges in standardization, evidence, safety, and production scalability.
42 citations
,
June 2021 in “Pharmaceutics” This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.
92 citations
,
April 2021 in “Pharmaceutics” This review discusses the applications and challenges of lipid nanosystems in various fields, comparing techniques for evaluating nanoparticle properties, and reports no new experimental results.
91 citations
,
August 2024 in “Acta Pharmaceutica Sinica B” This review explores how microneedles can improve the delivery of dermatological treatments by bypassing the skin's outer barrier, discussing their potential use in managing skin diseases, cosmetic applications, and challenges related to clinical adoption.
63 citations
,
February 2010 in “Journal of Neurophysiology” This study observed that electrical stimulation of specific mechanoreceptive afferents in the orofacial region can evoke sensations consistent with their response properties, while others may require multiple afferents to access perceptual levels.
9 citations
,
June 2025 in “Frontiers in Pharmacology” This review highlights recent advancements in microneedle technology, noting its ability to enhance transdermal drug delivery, biosensing, cancer treatment, and skin disease repair, while emphasizing its potential for improving patient compliance and reducing side effects.
June 2022 in “Scientific Reports” This study found that prevelex coatings on microwell array devices enhanced the formation of uniform cell spheroids and enabled the development of hair follicles in tissue engineering applications.
90 citations
,
October 2023 in “Advanced Drug Delivery Reviews” This review highlights that unresolved inflammation is a major issue in diabetic foot ulcers and discusses emerging biomaterials-based strategies to modulate the inflammatory response, potentially aiding in tissue regeneration and healing in these chronic wounds.
24 citations
,
August 2021 in “Scientific Reports” This study found that non-thermal atmospheric pressure plasma may stimulate hair growth through activation of the Wnt/β-catenin signaling pathway, suggesting it could be a potential non-pharmacological treatment for alopecia.
32 citations
,
June 2024 in “Pharmaceutics” This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.
9 citations
,
November 2024 in “Journal of Wound Management Official journal of the European Wound Management Association” Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
61 citations
,
September 2024 in “Micromachines” This paper provides a comprehensive overview of the applications of electrospun nanofibers in non-invasive medical fields, highlighting their potential for health monitoring, personal protection, thermal regulation, and wound care, and discusses the challenges and future development paths for this technology.
4 citations
,
January 2026 in “Micro” This review introduces a framework to integrate bioinspired conductive materials and advanced 3D/4D printing in regenerative medicine for dynamic, responsive tissue regeneration, emphasizing the potential of smart scaffolds to adapt to physiological cues.
216 citations
,
February 2022 in “Nanomaterials” This review discusses the potential of electrospun gelatin-based nanofiber dressings for wound healing and skin regeneration, detailing their properties, enhanced functionalities through crosslinking and bioactive components, and their application in treating challenging wound types like burns and diabetic wounds.
31 citations
,
August 2023 in “ACS Applied Bio Materials” This study developed granular hydrogels with reversible interparticle cross-linking, finding they offer high mechanical stability and enhance cell recruitment, making them promising for injectable and 3D printable scaffolds in tissue engineering and therapeutic delivery.
13 citations
,
November 2022 in “Chemical Science” This review discusses the use of inorganic-based biomaterials for hemostasis and wound healing, including various preparation methods and mechanisms, but reports no new clinical results.
September 2025 in “Biomolecules” This review analyzed the complex interactions within the skin microenvironment that influence hair follicle development and regeneration, exploring its role in hair-related disease treatment and highlighting research challenges and future directions.
April 2025 in “Experimental Eye Research” In this study, researchers characterized the retinal structure and function of the Oatrhg mouse model of gyrate atrophy, finding localized atrophy without significant retina-wide functional impact, suggesting the model may be useful for testing new treatments using multimodal retinal imaging.
March 2025 in “Journal of Cutaneous and Aesthetic Surgery” This study highlights promising advancements in non-invasive techniques for treating hair-related conditions, emphasizing the importance of customizing treatments based on individual needs.
39 citations
,
August 2005 in “Dermatologic surgery” This review describes the expanding medical uses of micropigmentation, including for vitiligo, burn scars, and nipple-areola reconstruction, and highlights safety concerns related to sterilization practices.
September 2025 in “International Journal of Biology Pharmacy and Allied Sciences” In this review, the authors examined the bioactive compounds in rosemary, noting its potential anti-inflammatory, antimicrobial, wound-healing, and anticancer activities, and highlighted its use in traditional medicine and cosmetics for conditions such as aging, baldness, and sun damage.
10 citations
,
May 2007 in “Journal of Prosthetic Dentistry” This clinical report describes a method for using tattoo marks to help align a facial prosthesis for a patient with skin flap reconstruction.