research Menopause and Aging: Quality of Life and Sexuality
Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
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research Significance of the S100A4 Protein in Psoriasis
The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
research The Effect of Menopause on the Skin and Other Connective Tissues
Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
research Barley Disease Susceptibility Factor RACB Acts in Epidermal Cell Polarity and Positioning of the Nucleus
RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.
research Distribution of P2X3-Immunoreactive Fibers in Hairy and Glabrous Skin of the Rat
P2X3-IR fibers are widespread in rat skin and likely help detect pain.
research Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire
Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
research An Ultrastructural Study of Hair Fiber Damage and Restoration Following Treatment with Permanent Hair Dye
Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.
research Pregnancy and the Skin
Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.
research Warfare-Related Craniectomy Defect Reconstruction: Early Success Using Custom Alloplastic Implants
Custom-designed implants effectively repaired skull damage in most soldiers injured in combat.
research The Upper Dermal Sheath Has Potential to Regenerate Hair in Rat Follicular Epidermis
The upper dermal sheath can regenerate hair in rats.
research Integral Lipid in Human Hair Follicle
The lipid in human hair follicles acts as a barrier, similar to the skin's lipid layer.
research Restoration of Hair Growth in Mice with an Alopecia Areata-Like Disease Using Topical Anthralin
Topical anthralin helped regrow hair in mice with a condition similar to human alopecia.
research Ancient Genomes Reveal the Evolutionary History and Origin of Cashmere-Producing Goats in China
Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.
research A Novel In Vivo Model for Evaluating Agents That Protect Against Ultraviolet A-Induced Photoaging
The study developed a novel in vivo model using transgenic mice to evaluate agents that protect against UVA-induced photoaging. This model used a human elastin promoter linked to a CAT reporter gene to measure elastin gene induction. It showed that PUVA treatment significantly increased promoter activation, which was reduced by sunscreens, particularly those with SPF 15 and UVA filters. The combination sunscreen provided the greatest protection, reducing CAT activity to near baseline levels. This model proved effective for rapidly identifying and comparing compounds that protect against UVA-induced photoaging, despite differences between murine and human skin responses.
research Mesotherapy for Local Fat Reduction
Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.
research Topical Tofacitinib Solution for the Treatment of Alopecia Areata Affecting Eyelashes
A woman's eyelash regrowth was successful using tofacitinib solution for alopecia areata.
research Dynamic Expression of Ornithine Decarboxylase in Hair Growth
The study demonstrated that ornithine decarboxylase (ODC) played a significant role in hair follicle development and hair growth by being associated with cell proliferation and commitment. ODC was expressed in embryonic epidermis at sites of follicle development and persisted in proliferating bulb cells of anagen follicles, except at the base of the bulb. Its expression decreased as follicles entered catagen and resumed with new follicle initiation. In vibrissae, ODC showed a complex expression pattern, being present in both the bulb and hair shaft, and in outer root sheath cells near the follicle bulge, suggesting a link to hair follicle stem cells.
research Synchronously Developing Collet Hairs in Arabidopsis Thaliana Provide an Easily Accessible System for Studying Nuclear Movement and Endoreduplication
Arabidopsis collet hairs are good for studying nuclear movement and DNA content increase during growth.
research Genetics of Structural Hair Disorders
The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Both gene and non-gene areas of DNA evolved to make some mammals hairless.
research Bioextracting Polyphenols from the Brown Seaweed Ascophyllum Nodosum from Québec's North Shore Coastline
Freezing brown seaweed right after harvesting and using microwave-assisted extraction with 75% 1,3-propanediol as a solvent is the best way to get polyphenols for cosmetics.
research Alopecia Areata in a Patient with Candidiasis-Endocrinopathy Syndrome: Unsuccessful Treatment Trial with Diphenylcyclopropenone
The treatment for alopecia areata with diphenylcyclopropenone was unsuccessful.
research Treatment of Cystathionine Beta-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector
MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
research Cartilage Oligomeric Matrix Protein Forms Part of the Connective Tissue of Normal Human Hair Follicles
A protein called COMP is part of the connective tissue in normal human hair follicles and may be important for hair health.
research Variant 1859G→A (Arg620Gln) of the Hairless Gene: Absence of Association with Papular Atrichia or Androgenetic Alopecia
Haplogroup X found in Altaian population supports Amerindian origin.
research Surgical Pearl: Mechanoanesthesia to Reduce the Pain of Local Injections
Using a vibrating device during injections can help reduce pain.
research Reactivation of Alopecia Areata After Dupilumab Therapy for Atopic Dermatitis
Dupilumab for skin problems might reactivate hair loss in some patients.
research Growth in Turface Clay Permits Root Hair Phenotyping Along the Entire Crown Root in Cereal Crops and Demonstrates That Root Hair Growth Can Extend Well Beyond the Root Hair Zone
Root hairs in cereal crops can grow beyond the usual zone, and using Turface® clay helps study this.
research Clinical, Histological, and Immunophenotypic Findings in a Mare with Mammary Lymphoma Associated with Anemia and Pruritus
A mare had severe symptoms and died from a large lymphoma.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.