11 citations
,
July 2015 in “Frontiers in Cellular Neuroscience” This study found that corticosterone promotes neurosteroid synthesis in hippocampal neurons, which can lead to ethanol-mediated synaptic dysfunction even at moderate ethanol levels, potentially contributing to stress-related cognitive impairment from alcohol.
11 citations
,
January 2013 in “International Journal of Trichology” This article reports a case of neurodermatitis where a combination of intralesional steroids, oral doxepin, and psychotherapy resulted in complete symptom remission and hair regrowth, highlighting the importance of addressing emotional factors in treatment.
11 citations
,
November 2011 in “Neuroreport” In this study, paroxetine's antihyperalgesic effect in a rat model of neuropathic pain was shown to be mediated by increased levels of the neurosteroid allopregnanolone in the spine.
11 citations
,
October 2011 in “Allergologia et immunopathologia” A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.
11 citations
,
September 2011 in “Biochemical journal” This study found that neurotrophin-4 regulates Cav3.2 T-current expression in D-hair neurons via TrkB receptor activation, highlighting its role in mechanosensitive function.
11 citations
,
October 2010 in “Behavioural Brain Research” This study found that neonatal administration of allopregnanolone enhances, while finasteride suppresses, the effects of adult intrahippocampal pregnenolone sulphate on rat locomotor activity in an open field test.
11 citations
,
March 2010 in “PubMed” This study concluded that monthly pulse IV cyclophosphamide therapy was effective in achieving complete or partial remission in 68.9% of Indian patients with severe lupus nephritis, though longer follow-up is needed.
11 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Hair transplant and applying 5% minoxidil solution can effectively treat permanent hair loss, but it may change hair direction in some cases.
11 citations
,
July 2007 in “Journal of Hepatology” This study found a high prevalence of nonalcoholic fatty liver disease among women with polycystic ovary syndrome, with 41% of the participants affected.
11 citations
,
November 1991 in “Journal of Neuropathology & Experimental Neurology” This study found that brindled mottled mice, a model of Kinky hair syndrome, exhibited abnormal development of catecholamine neurons, with increased TH-immunoreactive neurons and altered neurochemical profiles compared to controls.
10 citations
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May 2018 in “Nutrition and Cancer” This article reviews current research on spice-derived nutraceuticals for treating melanoma and skin cancer, noting emerging evidence that these natural substances may offer preventative and protective benefits against cancer, amidst increased global interest.
10 citations
,
January 2012 in “Lupus” This case report is the first to associate NEMO syndrome with systemic lupus erythematosus, suggesting a potential role for NF-kB essential modulator in the pathogenesis of SLE.
10 citations
,
July 2011 in “Wound Repair and Regeneration” This article proposes several potential approaches for scar prevention and therapy, including anti-transforming growth factor-β strategies and tissue-engineered skin, but reports no new clinical results.
10 citations
,
September 2024 in “Neural Regeneration Research” This study found that using induced pluripotent stem cell-derived mesenchymal stem cells with acellular nerve allografts significantly improved axon regeneration and functional recovery in rats with sciatic nerve injuries, suggesting a promising approach for clinical nerve repair therapies.
10 citations
,
August 2024 in “Neuroscience & Biobehavioral Reviews” This review discusses the role of neuro(active)steroids, particularly those in the 5α reductase pathway, in modulating dopamine signaling and their impact on neuropsychiatric disorders characterized by dopamine imbalances, including addiction, schizophrenia, and Parkinson's Disease.
10 citations
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July 2023 in “Pharmaceuticals” This study explored the wound healing potential of a natural marine soft coral-derived nanoparticle-based gel in a diabetic excision wound model, finding it effectively regulates proinflammatory cytokines and inhibits enzymes related to wound healing.
10 citations
,
September 2022 in “Psychiatry and Clinical Neurosciences” This review discusses post-acute sequelae of SARS-CoV-2 infection, highlighting the challenges in diagnosing and managing the variety of persistent symptoms, and reports no new clinical results.
10 citations
,
January 2020 in “Biomedicine & Pharmacotherapy” This study found that XiaoZhenFang (XZF) reduced skin toxicities caused by Erlotinib in a mouse model, likely through mechanisms involving inflammation and EGFR-related pathways.
10 citations
,
May 2018 in “Neuropharmacology” This study suggests that inhibitors of steroidogenic enzymes may have therapeutic potential for certain behavioral disorders linked to dopaminergic hyperfunction, despite concerns about their endocrine impacts.
10 citations
,
May 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that altering neurosteroid levels during early development in male rats can influence KCC2 levels, underscoring the role of neurosteroids in hippocampal maturation.
10 citations
,
January 2014 in “BioMed research international” In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.
10 citations
,
February 2013 in “PLoS ONE” This study found that neprilysin (NEP) activity and expression play a significant role in regulating the hair cycle in rats, with a specific inhibitor suppressing hair growth in mice.
10 citations
,
July 2011 in “British Journal of Dermatology” This study found that brain-derived nerve factor protein expression was significantly increased in balding scalp samples from men with androgenetic alopecia, suggesting it may play a role in hair follicle regulation.
10 citations
,
July 2011 in “Archives of Pharmacal Research” 10 citations
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May 2007 in “British Journal of Dermatology” This case report describes the first known instance of congenital follicular mucinosis in a newborn, diagnosed through histopathological examination of a scalp lesion.
10 citations
,
January 1992 in “Screening” This study concluded that newborn screening for biotinidase deficiency effectively identified cases and likely prevented irreversible complications from the disorder in some infants.
9 citations
,
February 2025 in “Journal of Nanobiotechnology” In this study, researchers found that using bioinspired nanovesicles derived from inflammation memory-activated epidermal stem cells effectively promoted healing in diabetic wounds by reprogramming neutrophils to an anti-inflammatory phenotype in both laboratory and animal models.
9 citations
,
August 2023 in “Antioxidants” This study found that Gelidium corneum, a type of red seaweed, may serve as a promising source of bioactive compounds for skin health, showing photoprotective and healing properties in vitro and antioxidant and stability benefits in vivo when used in dermocosmetic formulations.
9 citations
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May 2023 in “Inflammation Research” This study reported that new drugs, despite lower specificity compared to certain immunobiological therapies, are effective across various challenging dermatological diseases, such as psoriasis, psoriatic arthritis, atopic dermatitis, alopecia areata, and vitiligo.
9 citations
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April 2021 in “Annals of Translational Medicine” This study observed that facial feminization surgery significantly improved facial appearance and alleviated gender dysphoria among Chinese transgender females, with all patients expressing satisfaction post-surgery.