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A new microneedle system effectively delivers finasteride to treat hair loss.

In this study, synthesized composite nanocarriers containing ribose and peptides demonstrated enhanced transdermal delivery, improved uptake by skin cells, promoted cell proliferation, enhanced antioxidant enzyme activities, and increased autophagy, suggesting a potential for more effective skin anti-aging treatments.

In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.

The researchers reported that using exosomes from hair follicle stem cells with acellular nerve allografts helped bridge facial nerve defects in rats and may match the effectiveness of autograft therapy.

In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.

This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.

Nanocrystals improve alopecia areata treatment by better targeting hair follicles.

This review discusses the role of neural crest stem cell-like states in adult neural crest-derived tissues, suggesting they may contribute to tissue repair by generating new cell types and activating repair programs.

This case report describes a five-year-old boy diagnosed with nevus comedonicus syndrome, a rare skin condition, characterized by asymptomatic skin lesions and a congenital cataract of the right eye, without inflammation or typical signs of related conditions.

This review discusses the role of keratinocytes in hidradenitis suppurativa, highlighting their genetic and metabolic influences on disease progression without presenting new clinical results.

This review examines the role of autoinflammation and immune dysregulation in hidradenitis suppurativa, linking it to genetic factors and autoinflammatory syndromes, but highlights the need for further research to fully understand its pathogenic mechanisms.

In this study, secondary syphilis presented diverse clinical manifestations, with syphilitic alopecia occurring only in HIV-positive patients, underscoring the importance of considering syphilis in differential diagnoses for vulnerable populations.

This study developed a peptide-based topical delivery system that enhanced hair growth with reduced systemic exposure to finasteride, showing efficacy comparable to 5% minoxidil in vivo while using significantly less finasteride than oral doses.

This study found that skin is a significant site for estrogen production in mice, impacting both hair cycle regulation and sensitivity to chemical carcinogenesis.

In this research, experienced clinicians noted inconsistency in the reproducibility of the commonly used Hamilton-Ludwig scales for assessing pattern hair loss severity in photographic assessments, leading to the proposal of a new 5-point scale for staging female hair loss.

In this study, researchers analyzed English primary care data and found that long-COVID symptoms such as fatigue, cognitive, and mobility impairments persisted at 6–12 months after infection, though these effects were generally less pronounced following the later pandemic wave.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

This study found that macroscopic vesiculobullous lesions with epidermal devitalization in dogs are part of the clinical spectrum of canine cutaneous epitheliotropic T-cell lymphoma.

This study suggests that Demodex mites might universally inhabit adult humans, with a phylogenetic analysis indicating potential undiscovered lineages of the D. brevis species based on geographic differences.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

This study found that in Arabidopsis seedlings, tonoplast intrinsic proteins are targeted to the vacuole via at least two pathways, including pathways with differing sensitivity to a chemical inhibitor that affect root hair growth and PIN2 targeting.

This study found that the effectiveness of 17-beta-estradiol in inhibiting hair growth depends on its application method, and noted significant sex differences in response to 17-alpha-estradiol in male and female mice.

This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.

In this study, an injectable hydrogel incorporating antibacterial agents was shown to effectively heal wounds and promote hair follicle and capillary regeneration, offering a promising approach for skin tissue engineering.

This study reports that generalized discoid lupus erythematosus is a recognized canine variant of cutaneous lupus erythematosus, resembling its human counterpart, with varied treatment responses and common relapses.

This case report describes how a long-term combination of oral fatty acids and topical therapy appeared beneficial for managing autosomal recessive congenital ichthyosis in a goldendoodle with a PNPLA1 mutation.

Among in vitro and in vivo models, this study found that Miscanthus sinensis var. purpurascens flower extract may promote hair growth, potentially by modulating growth factor expressions and facilitating earlier hair follicle transitions in treated mice.

This study suggests that Annexin A2 isoform 2 might play a role in regulating the proliferation and growth of dermal papilla cells, potentially impacting the hair follicle growth cycle.

This review examines the diversity and role of stem cells in the adult dermis, noting a lack of precise understanding about their hierarchy and relationship to dermal fibroblast subpopulations, and reports no new results.

This review discusses current and potential approaches using stem cells for treating hypopigmentation disorders like vitiligo but does not present new clinical findings.