141 citations,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
116 citations,
December 2013 in “European journal of endocrinology” Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.
108 citations,
November 1980 in “British Journal of Dermatology” Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
100 citations,
March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.
88 citations,
June 2016 in “Human Reproduction Update” New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
82 citations,
December 2015 in “Nanomedicine” Nanoparticle systems make cancer treatment less toxic.
78 citations,
March 2004 in “Annals of Oncology” The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.
73 citations,
May 1976 in “JAMA” Long-term parenteral nutrition without zinc can cause severe zinc deficiency.
64 citations,
July 2011 in “Dermatologic Therapy” Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
63 citations,
February 2013 in “Human cell” PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.
60 citations,
June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
56 citations,
January 2019 in “Lancet” JAK inhibitors help regrow hair in alopecia areata patients, improving their quality of life.
55 citations,
December 2006 in “Journal of The American Academy of Dermatology” Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.
52 citations,
February 1985 in “Archives of Dermatology” Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
51 citations,
May 2011 in “Phytotherapy Research” Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
50 citations,
February 2018 in “Biomedicine & pharmacotherapy” Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
50 citations,
December 1999 in “British Journal of Dermatology” Finasteride improves hidradenitis suppurativa but not for child-bearing women.
43 citations,
February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
42 citations,
January 2007 in “Pediatric dermatology” Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.
39 citations,
October 2014 in “Schweizerische medizinische Wochenschrift” Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.
28 citations,
March 2017 in “Scientific Reports” Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
26 citations,
April 2007 in “Journal of pediatric gastroenterology and nutrition” A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.
24 citations,
February 2007 in “International Journal of Dermatology” A woman with cervical cancer had rare scalp metastasis causing a unique type of hair loss.
23 citations,
September 2017 in “Journal of the American Academy of Dermatology” Apremilast did not work for treating severe alopecia areata.
22 citations,
January 2015 in “The Cochrane library” DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
21 citations,
May 2021 in “Prostate Cancer and Prostatic Diseases” COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
21 citations,
October 2018 in “European Journal of Pharmacology” Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.
18 citations,
January 1992 in “The Journal of emergency medicine” Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.
16 citations,
March 2011 in “Pediatric diabetes” Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
15 citations,
June 2018 in “Food Reviews International” Pumpkin seed oil may improve prostate health, bladder control, and hair growth in men.