431 citations,
October 2008 in “Current Medicinal Chemistry” Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
51 citations,
June 2021 in “Signal Transduction and Targeted Therapy” The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
10 citations,
July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
71 citations,
May 1991 in “Clinical and Experimental Dermatology” Young men with male pattern baldness lose hair density over time without treatment.
46 citations,
September 2011 in “Journal of Endocrinology” Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
44 citations,
March 2016 in “Frontiers in cellular neuroscience” Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.
36 citations,
May 2021 in “Nutrients” Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.
28 citations,
January 2000 in “Medical Mycology” Fungal infections in lab animals can interfere with research.
24 citations,
September 2011 in “Autoimmunity” Natural killer cells play a key role in autoimmune skin diseases like pemphigus vulgaris.
24 citations,
January 2006 in “Skin Pharmacology and Physiology” Finasteride reverses early hair loss and promotes growth.
20 citations,
January 2022 in “Polymers” Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.
15 citations,
October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
14 citations,
October 2020 in “Natural Products and Bioprospecting” Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
11 citations,
December 2018 in “Assay and Drug Development Technologies” Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
9 citations,
October 2008 in “British Journal of Dermatology” The growth of the Epstein-Barr virus in the patient's cells was linked to the worsening of her lymphoma.
8 citations,
January 2020 in “Skin appendage disorders” Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.
7 citations,
December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
7 citations,
January 1990 in “Clinical and Experimental Dermatology” Hair loss gradually happens, and minoxidil helps regrow hair.
5 citations,
January 2014 in “Advances in bioscience and biotechnology” Natural honey protects against Doxorubicin's harmful effects.
3 citations,
January 2019 in “Journal of Dermatology” The p.P25L mutation in the KRT5 gene causes a rare skin condition that worsens over time and may lead to hair loss starting in young adulthood.
3 citations,
December 2015 in “Asian journal of dermatology” Natural plant extracts with sweet flag can significantly reduce hair loss and increase hair density and thickness in people with alopecia.
3 citations,
July 2015 in “International journal of pharmacology” Natural plant extracts help prevent hair loss and promote hair growth.
2 citations,
May 2023 in “Frontiers in Pharmacology” Natural products may help treat skin inflammation from abnormal adrenal hormones.
2 citations,
January 2022 in “Dermatologic Therapy” Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.
2 citations,
March 2009 in “Hair transplant forum international” Men generally have a certain thickness of hair at their hairline.
2 citations,
January 2009 A natural extract-based hair growth product was developed and showed promise in preliminary tests.
2 citations,
October 1990 in “PubMed” Severe alopecia areata involves higher levels of certain immune cells, which can be normalized with betamethasone.
1 citations,
July 2023 in “Plastic and Aesthetic Nursing” Biotin and collagen may improve hair health.
January 1997 in “Cosmetics and toiletries” A meadowfoam seed oil derivative can penetrate and repair human hair.
November 2024 in “GSC Biological and Pharmaceutical Sciences” Black mulberry may promote hair growth and improve scalp health.