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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Soy isoflavones can protect lung tissue from radiation damage.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

FLCN helps control iron levels in cells.

Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.

Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

RTA 408 cream protects mice from radiation skin damage.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

Hair from balding and non-balding areas regrows similarly on mice.

Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.