research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
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research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Mitoxantrone
Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
research Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy
Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
research 6-Gingerol Inhibits Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice
6-Gingerol, found in ginger, may slow down hair growth and could be used for hair removal.
research Regeneration of Fat Cells from Myofibroblasts During Wound Healing
Some wound-healing cells can turn into fat cells around new hair growth in mice.
research Bendamustine in Indolent Non-Hodgkin's Lymphoma: A Practice Guide for Patient Management
Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.
research Power Boosting the Grafts in Hair Transplantation Surgery
A new storage solution may increase hair transplant graft survival.
research Secretory Phospholipase A2-IIA Overexpressing Mice Exhibit Cyclic Alopecia Mediated Through Aberrant Hair Shaft Differentiation and Impaired Wound Healing Response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research Clinical Use of a Protein-Sparing Modified Fast
The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.
research Current Advances of Dendrobium Officinale Polysaccharides in Dermatology: A Literature Review
Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.
research Tissue Regenerative Delays and Synthetic Lethality in Adult Mice After Combined Deletion of ATR and TRP53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research An Ovol2-Zeb1 Transcriptional Circuit Regulates Epithelial Directional Migration and Proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research Recent Developments in the Treatment of Obesity with Particular Reference to Semistarvation Ketogenic Regimens
The document concludes that a high-protein, low-carb diet can lead to significant weight loss but requires caution and further research.
research Medication Repurposing: New Uses for Old Drugs
Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Cutaneous Manifestations of Polycystic Ovary Syndrome: A Cross-Sectional Clinical Study
Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.
research B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance
B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
research Sulforaphane Mobilizes Cellular Defenses That Protect Skin Against Damage by UV Radiation
Sulforaphane from broccoli can help protect skin from sun damage.
research Age-Associated Inflammation Connects RAS-Induced Senescence to Stem Cell Dysfunction and Epidermal Malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research Vitamin D Receptor, UVR, and Skin Cancer: A Potential Protective Mechanism
Vitamin D receptor may help protect against UV-induced skin cancer.
research Hair Growth-Promoting Effect of Carthamus Tinctorius Floret Extract
Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.
research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
research Birt-Hogg-Dubé Syndrome: From Gene Discovery to Molecularly Targeted Therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models
Guilu Erxian Glue may help reduce chemotherapy side effects like weight loss and heart stress.
research Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
research Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase
Minoxidil boosts hair growth by increasing blood flow and nutrients to hair follicles.
research Epidermal Stem Cell Fate: What Can We Learn from Embryonic Stem Cells?
Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.