November 2025 in “Stem Cell Research & Therapy” In this study, the authors reported that combining PMSC-secretome and Wnt10b in a GelMA hydrogel scaffold promoted effective hair follicle biofabrication and hair growth in a small in vivo experiment. They emphasized the need for larger studies to confirm these results.
November 2025 in “The Journal of Immunology” This study identified specific genes upregulated in skin γδ T cells involved in alopecia areata, with findings suggesting these cells contribute to disease pathogenesis through inflammatory and Th1 response mechanisms in mouse and possibly human skin.
October 2025 in “Journal of Translational Medicine” This literature review discusses the challenges and potential strategies for creating fully functional hair follicles capable of active cycling, emphasizing the molecular mechanisms, signaling pathways, and innovative regenerative techniques, such as hair micropatterning and three-dimensional printing, crucial for optimizing hair follicle regeneration.
October 2025 in “Journal of Drug Delivery and Therapeutics” In this review, the researchers compared the traditional use of Senna Makki in Unani medicine for various ailments to modern pharmacological evidence, endorsing its role as a laxative but indicating further research is needed for its efficacy in other therapeutic areas.
October 2025 in “Scientific Reports” This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.
September 2025 in “Romanian Journal of Medical Practice” In this study of women with female pattern hair loss, iron deficiency was associated with the condition due to significantly lower serum ferritin and altered hematological indices compared to healthy controls, while no significant differences in serotonin levels or renal function were observed.
September 2025 in “Animals” In this study, dermatophytosis was prevalent among 52% of dogs and 70% of cats with skin lesions, with younger animals facing higher infection risks; combined itraconazole, clotrimazole, supportive care, and vaccination led to the fastest recovery.
September 2025 in “Cell Biochemistry and Function” In this study, ZnO nanoparticles synthesized with Ferulago angulata extract and doped with magnesium showed improved antioxidant, antibacterial, and antifungal properties, and facilitated faster wound healing and hair growth in a burn treatment model, although higher concentrations decreased cell viability.
August 2025 in “مجلة جامعة الحضارة للبحوث التطبيقية والإنسانية” This study conducted in Yemen involving 50 patients found that tissue expansion was effective for correcting scars and defects from post-burn and post-war injuries, achieving a 78% satisfaction rate with minimal complications.
July 2025 in “Journal of Cosmetic Dermatology” In this clinical study involving individuals with localized alopecia areata, TrA injections were found to significantly outperform MTX, leading to better hair regrowth and higher patient satisfaction, though both treatments had similar mild side effects.
July 2025 in “Pakistan Journal of Medicine and Dentistry” This study found a significant association between smoking and both the presence and severity of androgenetic alopecia among adult males, suggesting that smoking may be a modifiable risk factor for this common form of hair loss.
July 2025 in “The Lancet Regional Health - Southeast Asia” This Health Policy report outlines the creation of evidence-based clinical practice guidelines and referral pathways for managing dermatological conditions in Pakistan's primary care setting, aiming to standardize care and improve patient outcomes.
July 2025 in “Journal of Dermatology Research Reviews & Reports” This review explores how exosomes can be used therapeutically in autoimmune skin diseases, emphasizing that their properties like stability and biocompatibility make them promising for targeting immune signaling pathways involved in conditions such as inflammation and scleroderma.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” This review reports that the human amniotic membrane has promising regenerative, anti-inflammatory, and antimicrobial properties, suggesting its potential for innovative clinical applications in dermatology, such as wound healing and psoriasis treatment, as well as aesthetic uses like skin rejuvenation and hair regeneration.
In this case study, a nine-year-old boy with alopecia universalis following severe chickenpox showed complete hair regrowth after treatment with tofacitinib, suggesting the drug's potential in managing varicella-zoster virus-induced alopecia by modulating immune responses.
May 2025 in “Egyptian Journal of Dermatology and Venerology” This study found that specific SNPs in the CYP19A1 gene were associated with Female Pattern Hair Loss in Egyptian women, with altered CYP19A1 gene expression and higher frequencies of related genotypes observed in patients compared to controls.
March 2025 in “Anatomy & Cell Biology” This study found that hair follicle stem cell-derived secretome mitigated cell death, apoptosis, and inflammation while upregulating neurotrophic factors in astrocytes exposed to oxygen-glucose deprivation, an in vitro ischemic stroke model, suggesting potential therapeutic benefits in stroke recovery.
March 2025 in “Yemeni Journal For Medical Sciences” This study found that 89.3% of female college students in Aden, Yemen, had hypovitaminosis D, with sunscreen use and lack of vitamin D supplements significantly associated with this condition.
March 2025 in “International Journal of Trichology” This study found that, in female patients with pattern hair loss, injections of adipose-derived stem cells increased hair density and thickness, reduced perifollicular inflammation, and enhanced markers associated with hair cycle regeneration.
February 2025 in “Journal of Clinical Investigation” This study found that RNase L acts as a regeneration repressor gene in mammals, as seen in Rnasel-/- mice which showed increased regenerative capacity and elevated Wound Induced Hair Neogenesis through enhanced IL-36α signaling, suggesting a tradeoff between regeneration and immune regulation.
February 2025 in “The Egyptian Journal of Medical Microbiology” In this study, zinc oxide nanoparticles combined with Carbomer940 hydrogel significantly accelerated wound healing and hair growth in Balb/c mice, showing a 56.9% increase in wound closure rate compared to MEBO ointment and control groups, without causing damage or infection.
January 2025 in “Indian Journal of Unani Medicine” This case study observed that a Unani medicine regimen significantly improved hair shedding and quality of life in a 24-year-old female with Telogen Effluvium following a febrile illness, showing potential effectiveness and safety in this context.
January 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” This review discusses the various off-label treatments for alopecia areata, highlighting that these therapies may promote hair growth but are not curative.
This study reports that alternative cancer clinics spent over $15 million on Google ads in the past decade, directing 44.4% of their website traffic from these ads, which targeted sensitive search queries of cancer patients seeking alternative treatments.
November 2024 in “Indus journal of bioscience research.” In this animal study, funnel seed extract significantly reduced insulin and testosterone levels and increased ovulating hormones in rats with induced polycystic ovarian syndrome, suggesting potential hormone-regulating properties.
October 2024 in “JEADV Clinical Practice” This study reports the prescribing preferences of UK dermatologists for treating various hair loss conditions, noting that topical corticosteroids for mild to moderate alopecia areata and topical minoxidil for female pattern hair loss are commonly used first-line treatments.
September 2024 in “Advanced Biomedical Research” In this study, chick embryo extract enhanced neuronal differentiation and trophic factor expression in rat hair follicle stem cells, suggesting potential improvements for stem cell therapies in neurodegenerative diseases.
July 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This review highlights the increasing use of trichoscopy, a noninvasive and well-tolerated diagnostic tool, to aid in the accurate diagnosis and management of various pediatric hair and scalp conditions, such as alopecia and other abnormalities.
July 2024 in “Clinical Case Reports” This study suggests that young females may experience a rare coexistence of Frontal Fibrosing Alopecia and ophiasis pattern Alopecia Areata, possibly sharing a common underlying pathophysiology.
June 2024 in “Regenerative Therapy” This review highlights the potential of exosomes as a novel therapeutic approach for skin diseases and aging, due to their stability, transportability, and ability to carry various bioactive compounds to target cells.