June 2026 in “Journal of Cosmetic Dermatology” This study found that patients with frontal fibrosing alopecia had higher hair shaft concentrations of titanium, zinc, aluminum, and iron, possibly linked to the use of metal-containing products.
June 2026 in “Materials Today Communications” This study reported that a newly designed multifunctional conductive hydrogel, PrM, combined with electrical stimulation significantly accelerated wound healing, achieving 95.9% healing in a mouse model on day 10, by enhancing regenerative processes and downregulating TNF-α signaling under electrical treatment.
May 2026 in “Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology” The researchers reported that zinc carbonate nanoparticles stabilized with polyvinylpyrrolidone did not show local irritant or skin-resorptive effects in preclinical tests on rabbits and rats.
May 2026 in “Journal of Health Sciences and Medicine” This study found that biotinoyl tripeptide-1-loaded solid lipid nanoparticles significantly improved thermal protection in hair, enhancing cuticle integrity and resistance to heat damage, compared to control samples.
May 2026 in “Colloids and Surfaces B Biointerfaces” April 2026 in “ACS Applied Materials & Interfaces” In this study, Sper-12/siRNA nanoparticles effectively suppressed abnormal AR protein levels, promoted hair follicle proliferation, and alleviated hair loss symptoms in androgenetic alopecia model mice, providing a promising delivery platform for siRNA-based therapeutics.
In this study, researchers developed a novel bio-patch from decellularized freeze-dried tumor tissues and hair melanin nanoparticles, which demonstrated enhanced wound healing in vivo by reducing oxidative stress, suppressing inflammation, and promoting angiogenesis.
January 2026 in “New Journal of Chemistry” This study synthesized calcium citrate nanoparticles to improve the solubility and reduce the irritation of minoxidil solutions for treating androgenetic alopecia.
January 2026 in “Journal of Nanomaterials” January 2026 in “International Journal of Biomedical Investigation” This review reported that green-synthesized metallic nanoparticles from agricultural waste hold promise for improving chronic wound care due to their antimicrobial, antioxidant, and regenerative properties, though challenges like biosafety and manufacturing scale need addressing for clinical use.
September 2025 in “Al-Nahrain Journal of Science” In this research, the authors found that green-synthesized zinc oxide nanoparticles (GS-ZnONPs) exhibited antibacterial activity against Staphylococcus species isolated from alopecia patients, but also showed cytotoxic effects on human dermal fibroblast cells at a 400 mg/mL concentration.
July 2024 in “Journal of Investigative Dermatology”
November 2023 in “Journal of Basic Microbiology” This study explored the fungal diversity on human scalps, identifying 15 genera and 24 species from 18 scalp samples of girls, with yeast-like structures found in 33.3% of cases. Additionally, zinc oxide nanoparticles, synthesized using ginger extract, showed significant antifungal activity against specific species.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, exosome-like nanoparticles derived from rose stem cell culture were found to enhance skin quality by increasing collagen production, reducing melanin and inflammation, and promoting cell migration in vitro, suggesting potential aesthetic applications.
Ashwagandha-derived nanoparticles can promote human hair growth.
April 2023 in “Journal of Investigative Dermatology” This study examined Ashwagandha-derived exosome-like nanoparticles and found that they increased hair growth markers and hair shaft production in human hair follicles ex vivo, suggesting potential for plant-derived exosome therapies in hair loss treatments.
November 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews the potential of nanotechnology, particularly silver nanoparticles, to reduce the toxicity and side effects of cancer drugs, without reporting new clinical results.
October 2017 in “Doctoral thesis, UCL (University College London).” This study developed and tested nanostructured lipid carriers for topical dutasteride delivery, finding them stable, low in cytotoxicity and non-irritating, with no drug permeation through pig ear skin over 48 hours.
January 2016 in “한국공업화학회 연구논문 초록집” This study modified nanocomposites with citric acid and hydrazine for potential dual use in cancer imaging and treatment, suggesting they might reduce side effects of traditional chemotherapy.
January 2011 in “Hebei yixue” This study found that 0.1% concentrations of finasteride-loaded solid lipid nanoparticles showed high entrapment efficiency and homogeneity.
October 2022 in “Frontiers in Bioengineering and Biotechnology” This study demonstrated that in a mouse model of androgenic alopecia, PLGA-DUT/siAR@DPCM nanoparticles effectively delivered drugs to hair follicles, suppressed androgen-related targets, promoted cell proliferation, and showed significant therapeutic effects with minimal adverse effects, suggesting their potential for clinical application.
92 citations
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April 2021 in “Pharmaceutics” This review discusses the applications and challenges of lipid nanosystems in various fields, comparing techniques for evaluating nanoparticle properties, and reports no new experimental results.
81 citations
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February 2022 in “Bioactive Materials” This study reported the development of pH-responsive nanoparticles that effectively deliver vancomycin in a controlled manner, demonstrated enhanced antibacterial activity, and showed promise for clinical applications by targeting bacterial infection sites with programmable drug release.
26 citations
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July 2023 in “International Journal of Nanomedicine” The researchers suggest that combining microneedle technology with nanocarriers could enhance drug delivery systems for treating central neurological diseases due to nanoparticles' ability to prolong blood circulation time and improve brain targeting.
26 citations
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November 2022 in “European journal of medical research” This review discusses the potential of nanoparticles to modify angiogenesis processes for therapeutic applications and reports no new clinical results, highlighting challenges and future prospects in treating angiogenesis-related diseases.
20 citations
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March 2023 in “Drug Delivery and Translational Research” This study found that a lacticin 3147 solid lipid nanoparticle gel demonstrated potent and sustained antimicrobial activity against S. aureus, including MRSA, in ex vivo S. aureus-infected pig skin.
7 citations
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July 2019 in “International Journal of Molecular Sciences” This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
2 citations
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October 2024 in “Artificial Cells Nanomedicine and Biotechnology” This study found that silver nanoparticles synthesized using Lens culinaris extract exhibited potent anticancer activity against MCF-7, HCT-116, and HepG2 cell lines and significant antimicrobial effects against Klebsiella pneumoniae and Acinetobacter baumannii.
2 citations
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April 2022 in “Nusantara Bioscience” This study proposes a quick and sensitive method for detecting vancomycin using modified silver nanoparticles and shows promising results against Gram-positive and Gram-negative bacteria.
July 2026 in “Journal of Drug Delivery and Therapeutics” This study evaluated Finasteride-loaded nanostructured lipid carriers for topical use in treating androgenetic alopecia and found that these carriers offer sustained drug release and may reduce systemic side effects compared to oral administration.