This review highlights that nanotechnology offers promising avenues for enhancing drug delivery and developing new therapeutic strategies for androgenetic alopecia, though challenges remain in clinical translation and the need for long-term safety studies.
5 citations
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August 2023 in “Preprints.org” This review outlines recent advancements in droplet-based microfluidics used with food-grade materials to create delivery systems, emphasizing the design and function of systems like emulsions and microcapsules while discussing challenges related to scaling these processes from lab to industry.
4 citations
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May 2025 in “International Journal of Nanotechnology and Nanomedicine” This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.
April 2026 in “Nanomaterials” This perspective study suggests that plant-derived extracellular vesicles could advance the use of Ayurvedic medicinal plants in nanomedicine by enhancing their therapeutic potential and guiding future research.
December 2025 in “Sensors” In this review, recent advances in long-acting microneedle-based transdermal drug delivery systems are outlined, highlighting biodegradable polymers like PLA, PLGA, and PCL for sustained release and discussing challenges in clinical translation such as consistency in manufacturing and validating long-term efficacy and safety.
1 citations
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December 2023 in “Nanomaterials” In this study, the researchers synthesized copper-doped mesoporous silica nanoparticles and observed that they enhance tumor microenvironment regulation and, when paired with disulfiram, effectively kill cancer cells while also showing synergistic anti-tumor effects with immune checkpoint inhibitors.
43 citations
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February 2020 in “Clinica chimica acta” This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.
January 2024 in “Wiadomości Lekarskie” This research highlights major advancements in vaccinology, such as mRNA vaccines and nanoparticle delivery systems, enhancing vaccine efficacy and paving the way for novel vaccine development against infectious and non-infectious diseases like cancer, with implications for improved global health outcomes.
January 2024 in “Wiadomości Lekarskie” In this report, a case of a large primary extradural solitary fibrous tumor in the sacrum of a 31-year-old woman is detailed, where surgical treatment led to remission and improved functionality, despite the patient opting out of adjuvant radiotherapy to preserve fertility potential.
1 citations
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May 2025 in “Discover Chemistry.” This review highlights that although mangiferin, a polyphenol from the mango tree, faces challenges like low solubility and bioavailability, delivery vehicles such as nanoparticles and complexes have the potential to enhance its therapeutic effectiveness in treating various diseases.
49 citations
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February 2025 in “Science Advances” This review discusses the potential of biomimetic synthetic vesicles to advance precision diagnostics and medicine by combining the beneficial properties of naturally occurring extracellular vesicles and synthetic nanoparticles, although no new clinical results are reported.
8 citations
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August 2022 in “Pharmaceutics” This study found that erythrocyte-anchored CPA-encapsulated nanoparticles improved the delivery and accumulation of Cepharanthine in the lungs, enhancing its effectiveness in treating acute lung injury by reducing inflammatory responses.
3 citations
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March 2023 in “National Journal of Health Sciences” This article reviews the potential of platelet-rich plasma therapy in managing diabetic foot ulcers but reports no new clinical findings, highlighting the need for further controlled trials to evaluate its effectiveness.
29 citations
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April 2019 in “Acta neuropathologica communications” This study found that β-sitosterol, a brain-penetrable phytosterol, reduced melanoma cell growth and brain metastasis formation by interfering with mitochondrial respiration, suggesting its potential as an adjuvant therapy to BRAF inhibitors for patients with melanoma brain metastases.
3 citations
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September 2023 in “Advanced science” Researchers demonstrated that a new vaccine platform using antigen-loaded hydrogels enhanced humoral immune responses in mice, producing stronger antigen-specific antibody levels compared to the conventional adjuvant Alum, and offering promising protective capabilities against influenza virus.
January 2024 in “Wiadomości Lekarskie” This study outlines new strategies for overcoming "cold" tumors, which are typically unresponsive to cancer immunotherapy, with approaches like dendritic cell-based treatments and local immune microenvironment modification, bolstered by both preclinical and clinical trial data.
May 2026 in “International Journal of Drug Delivery Technology” This review highlights that nanotechnology enhances the solubility, stability, and bioavailability of phytochemicals from medicinal plants, improving their therapeutic efficiency in disease models like cancer and infections. However, it indicates that further research is necessary to optimize formulations and ensure safety for clinical use.
January 2026 in “Frontiers in Immunology” This review highlights icariin’s potential to regulate macrophages in varying conditions, discussing its effects on macrophage polarization, metabolism, and disease mechanisms, and noting the development of delivery systems to enhance its therapeutic impact.
2 citations
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December 2023 in “Pharmaceutics” This review highlights that direct drug delivery to the lungs for treating lung cancer may offer more precise targeting while reducing side effects compared to traditional methods.
86 citations
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August 2021 in “Polymers” This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.
20 citations
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August 2007 in “Molecular therapy” This study found that inducing hair follicles into the anagen-onset stage in mice enhances the immune response to a topically applied DNA vaccine against anthrax.
8 citations
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May 2023 in “Gels” This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.
5 citations
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July 2025 in “Nutrients” This study reviews how advancements in nanotechnology have improved food safety, nutrition delivery, and health interventions, but it also highlights the need for more research into safety evaluations and regulatory concerns.
2 citations
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October 2025 in “Chinese Medicine” This review article summarized the design, synthesis, and application of innovative delivery systems for berberine, highlighting their potential to enhance wound healing through improved bioactivity and bioavailability, particularly in challenging conditions like diabetic and infected wounds.
1 citations
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November 2020 in “Asian Journal of Pharmaceutical and Clinical Research” This review discusses the potential of nanotechnology in treating idiopathic pulmonary fibrosis by targeting abnormal alveolar epithelial cells and reports no new clinical results.
February 2026 in “International Journal of Molecular Sciences” This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.
May 2024 in “International Journal of Nanomedicine” This review examined the diverse therapeutic potentials of cannabinoids, highlighting their applications in pain, neurological, and cancer treatments, and emphasized the benefits of biodegradable polymers in improving drug delivery; however, further clinical trials are needed to fully explore these potentials.
57 citations
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January 2022 in “Biomedicines” This review outlines curcumin's dual role as a radiosensitizer in cancer cells and a radioprotector in healthy cells, drawing on recent experimental and clinical findings.
49 citations
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January 2023 in “Gels” This review summarizes recent advancements in three-dimensional bioprinting technology and hydrogel bioinks, highlighting their applications in tissue engineering, but reports no new experimental results.
16 citations
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January 2025 in “Burns & Trauma” This review highlights the promising potential of using nanomedicine-based immunotherapy in tissue regeneration, detailing recent advances in nanocomposite biomaterials and the modulation of immune responses to create optimal environments for tissue repair.