Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study developed a new finasteride release system using chitosan-based nanoniosomes, observing that 70% of the drug was released over ten days in vitro, suggesting potential for prostate cancer prevention.

This study found that liposomal formulations improved minoxidil delivery to skin layers compared to niosomes and a control solution, suggesting enhanced potential for topical hair loss treatment.

This study reviews various treatment options for androgenic alopecia, emphasizing the potential use of drug-loaded nanoparticles, but reports no new research results.

This review highlights the potential of drug-loaded extracellular vesicles as a promising drug delivery platform but notes that clinical translation faces challenges due to variability in methods and the need for standardization and safety evaluation.

This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.

This review discusses advancements in using dissolving microneedle systems for transdermal delivery of traditional Chinese medicine, highlighting potential benefits for simplifying application, enhancing safety, and increasing efficacy, and underscores its possible impact on modernizing traditional medicine practices.

This study's simulations revealed the complex "onion-like" organization of a lipid nanoemulsion droplet containing vitamins A and E for skin delivery, showing distinct concentration patterns of these vitamins within different layers of the nanodroplet.

This review discusses emerging cancer treatment methods focusing on cellular mechanisms unique to cancer cells and concludes no new clinical results.

This study found that low frequency sonophoresis may reduce percutaneous absorption of sodium fluorescein-loaded liposomes by partially blocking follicular pathways in the skin.

This review reports on the potential of non-viral and stimuli-responsive systems to improve CRISPR-Cas9 delivery for gene-editing therapies, highlighting recent progress with systems like lipid-based nanoparticles that enhance targeting specificity and stability.

This study found that dissolving microneedles loaded with platinum nanozymes induced faster hair growth in an androgenetic alopecia model than daily minoxidil applications, with no significant safety concerns.

This critical review highlights the anti-carcinogenic properties of luteolin, a plant flavonoid, and examines how encapsulating luteolin in nanoformulations may overcome its bioavailability challenges, potentially enhancing its effectiveness as a safer cancer treatment according to this source.

This study observed that proretinal nanoparticles delivered significantly higher concentrations of retinal to the stratum corneum and hair follicles compared to non-particulate forms, potentially improving topical retinoid therapy.

This study suggests that chitosan-enhanced human serum albumin nanoparticles could serve as a safe and effective carrier for delivering anticancer drugs like tamoxifen.

This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.

Smart microneedles improve hair loss treatment by delivering drugs precisely with fewer side effects.

In this study, researchers developed a leech-inspired microneedle platform for targeted delivery of metformin to hair follicle cells, which showed promising results in reducing inflammation and oxidative stress and promoting hair growth, offering a potential new treatment strategy for androgenetic alopecia.

This review highlights the potential of nanoparticle delivery systems to mitigate doxorubicin's adverse effects and enhance its effectiveness, while discussing the integration of nanotechnology with Streptomyces-derived compounds to potentially advance future cancer therapies.

This study found that a nanostructured lipid carrier gel containing Minoxidil and Finasteride met desired criteria for stability and performance, suggesting it may be an effective topical treatment for hair loss, especially in extreme conditions.

This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.

In this study, penetration of FA-PLGA nanoparticles into hair follicles was observed in excised dog, rat, and porcine skin, with the deepest penetration in porcine skin, suggesting its similarity to human skin for drug delivery studies.

This study reports that optimized PLA nanoparticles can effectively target hair follicles to deliver both lipophilic and hydrophilic compounds, suggesting potential applications in hair cosmetics and treatments.

This study developed a nitric oxide delivery system using PVA films and HA liposomes, which enhanced hair follicle vitality and repaired blood vessels in androgenic alopecia by promoting angiogenesis and reducing inflammation through the HIF-1 signaling pathway.

This study reported that newly developed minoxidil Pickering emulsion gels, designed using cellulose stabilizers, showed promising results for promoting hair regrowth and targeting hair follicles by enhancing the delivery and stabilization properties of the formulation in a hair loss treatment context.

The new minoxidil hydrogel improves delivery and is safe for treating hair loss.

Larger positively charged gelatin nanoparticles are more effective for delivering treatments to hair follicles.

This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.