29 citations
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April 2020 in “Biomolecules” This review discusses the potential biomedical and clinical applications of brassinosteroids, highlighting their observed antiviral, anticancerous, and other bioactivities in animal test systems, but reports no new findings.
25 citations
,
September 2020 in “Molecules” In this study, quercitrin was reported to promote hair growth and cell viability in cultured human dermal papilla cells by enhancing cellular energy metabolism and growth factor production via MAPK/CREB signaling.
25 citations
,
May 1994 in “Journal of Investigative Dermatology” This study identified a novel gene, hacl-1, that is specifically expressed in the hair follicles of ICR mouse skin and is associated with their active state.
24 citations
,
July 2016 in “Steroids” In this study using rat hippocampal cultures, progesterone and testosterone showed neuroprotective effects against oxygen-glucose deprivation-induced neuronal cell death, while metabolism of these hormones in the brain may affect their protective actions.
22 citations
,
May 2004 in “Tissue Engineering” This study found that collagen sponges with polyglycolic acid fibers support proper skin and hair follicle restructuring, suggesting potential usefulness for hair reconstitution research and clinical applications.
19 citations
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January 2016 in “Biological & Pharmaceutical Bulletin” This study found that Sargassum muticum extract and apo-9′-fucoxanthinone promoted hair growth in rat and mouse models by increasing dermal papilla cell proliferation and activating certain signaling pathways.
19 citations
,
July 2020 in “EBioMedicine” In this study, the researchers identified a variant in the CCHCR1 gene associated with an alopecia areata subtype characterized by impaired keratinization and autoimmune events.
18 citations
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March 2014 in “Journal of Pharmacological and Toxicological Methods” This study found that ovariectomized and finasteride-treated rats showed significant tear film deficiency and downregulation of sex steroid receptors in ocular tissues, suggesting potential models for studying dry eye disorders.
17 citations
,
July 2019 in “Scientific reports” This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.
15 citations
,
June 2015 in “Lasers in Medical Science” This study found that low-level laser therapy with an 830-nm wavelength most significantly stimulated hair growth in rats, compared to other wavelengths tested.
14 citations
,
September 2001 in “Archives of Dermatological Research” This study reported that Sonic hedgehog signaling is crucial for hair follicle development, with its expression being significantly induced in normal embryonic hair germs but inhibited in certain experimental models.
11 citations
,
August 2021 in “Stem Cell Research & Therapy” This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.
10 citations
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May 2019 in “BMC Complementary and Alternative Medicine” This study found that Bacillus/Trapa japonica fruit ferment filtrate extracts enhanced human hair follicle dermal papilla cell proliferation through the Akt/ERK/GSK-3β signaling pathway, suggesting potential benefits for alopecia treatment.
10 citations
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July 2019 in “Journal of Asia-Pacific Entomology” This study suggests that ultra-fine powders of steamed and lyophilized mature silkworms may have enhanced pharmacological effects compared to fine powders, possibly due to their smaller particle size.
10 citations
,
January 2018 in “International journal of trichology” This case report highlights the importance of histopathological examination in accurately diagnosing eruptive vellus hair cyst due to its rarity and resemblance to other conditions.
8 citations
,
January 2011 This study observed that a polyherbal ointment containing extracts from several plants promoted significant hair growth in rats compared to using single plant extracts.
7 citations
,
December 2020 in “ACS biomaterials science & engineering” In this study, researchers demonstrated that human hair keratins can self-assemble into stable nanofibrous networks in vitro, which are compatible with human skin cells and useful for regenerative applications.
7 citations
,
October 2018 in “South African journal of botany” This study found that the plant Clausena anisata exhibited promising antimicrobial, antioxidant, and anti-inflammatory activities against acne-causing bacteria and inflammation, suggesting its potential as a candidate for further anti-acne treatment research.
7 citations
,
June 2000 in “Journal of the American Academy of Dermatology” This study found that betamethasone valerate in a foam vehicle has comparable total coverage to traditional topical corticosteroid vehicles, despite less coverage per unit of foam.
6 citations
,
August 2021 in “International Journal of Pharmaceutics” This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.
4 citations
,
January 2010 in “Korean Journal of Family Medicine” This study found that newly diagnosed breast cancer patients in Korea have different hair mineral patterns, notably reduced zinc levels, which negatively correlate with body mass index compared to normal controls.
4 citations
,
October 2004 in “Humana Press eBooks” This chapter reports an organ culture method that permits mouse embryonic skin tissues to develop similarly to in vivo conditions, revealing that epidermal growth factor inhibits hair follicle formation.
4 citations
,
May 2020 in “Cureus” This case report describes an adult male from India with Werner's syndrome due to a novel homozygous mutation in the WRN gene, characterized by several premature aging symptoms.
4 citations
,
November 2017 in “The Journal of Dermatology” Sorafenib may cause hair loss in a way similar to alopecia areata.
4 citations
,
January 2013 in “PubMed” In this study, testosterone and finasteride were found to increase insulin and zinc levels while decreasing chromium levels in male adult rats, suggesting potential effects on the glucose cycle.
4 citations
,
November 2012 in “Dermatitis” A man got severe skin irritation after using marking nut sap for hair loss.
2 citations
,
January 2021 in “Applied Chemistry for Engineering” This review discusses the bioactive substances found in native Korean Pinus densiflora and koraiensis and highlights the need for more research on their industrial application, despite known physiological effects.
2 citations
,
November 2017 in “Food Additives & Contaminants: Part A” This study developed a validated method to detect prohibited drugs in dietary supplements, finding minoxidil, triaminodil, and finasteride in some samples.
2 citations
,
December 2022 in “International Journal of Infertility & Fetal Medicine” This study found that women with PCOS who are obese had an altered lipid profile and increased waist-hip ratio compared to lean counterparts, without differences in endocrine parameters.
2 citations
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January 2022 in “BioMed Research International” This study found that using an LED array with an 863 nm wavelength delayed tumor development and reduced systemic inflammatory cytokines in DMBA/TPA-induced mouse skin tumors, suggesting potential but limited benefits of light therapy.