101 citations
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August 2003 in “Journal of comparative neurology” In this study, naked mole-rats demonstrated unique skin and hair follicle innervation features compared to other species, suggesting adaptations to their subterranean environment and poikilothermy.
21 citations
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April 1982 in “Genetics Research” In this study, researchers observed that mice with the naked gene showed frequent absence of hair cuticle and cortical cells during follicle growth, with abnormal keratin deposition also noted.
12 citations
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August 1984 in “Genetics Research” In this study, researchers found that the naked (N) gene in mice indirectly affects the synthesis of structural proteins in mouse hair, resulting in reduced high tyrosine protein content and unusual amino acid compositions.
4 citations
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December 2017 in “American Journal of Dermatopathology” This study found that naked hair shafts significantly increased in cicatricial alopecias compared to non-cicatricial types, suggesting their potential use in diagnosing cicatricial alopecia.
2 citations
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January 1960 in “Australian Journal of Biological Sciences” The Naked gene in mice causes abnormal sebaceous glands and disrupts hair follicle organization.
This article describes the "naked" mouse mutation, which results in hair loss and is linked to chromosome 15, noting similarities and differences with human ectodermal dysplasia, but provides no new experimental findings.
75 citations
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October 2010 in “Mammalian genome” In this study, specific genetic polymorphisms in the KRT71 gene were associated with hairless and curly phenotypes in Sphynx and Devon Rex cats.
14 citations
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May 2019 in “Human gene therapy” This study found that minicircle-based gene therapy significantly lowered total homocysteine levels and improved liver CBS activity in a mouse model of CBS deficiency.
8 citations
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March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that the near-naked hairless mutation in mice is not an allele of the Hairless gene but may involve a mutation in a linked gene or a regulatory mutation.
March 2023 in “Journal of Student Research” This study indicates that the thermoregulatory hypothesis is most likely the main factor behind the evolution of hairlessness in humans.
103 citations
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March 2011 in “PLoS Biology” This study found that a mutation in the BMP12/GDF7 gene is associated with the Naked neck trait in chickens, reducing neck feathering due to altered signaling pathways.
40 citations
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February 1946 in “Canadian Journal of Research/Canadian journal of research” This study observed that the hair loss in homozygous rhino mice is associated with widening of the hair canal due to hyperkeratosis, leading to insufficient support for hair anchoring.
29 citations
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September 2014 in “American Journal of Dermatopathology” This study found that horizontal sections of scalp biopsies in patients with Central Centrifugal Cicatricial Alopecia often reveal follicular miniaturization, inflammation, and scarring, which can guide personalized treatment.
15 citations
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October 1976 in “Biochemical Journal” This study found that Naked trait mice exhibit a decrease in certain low-molecular-weight proteins in their hair, which contain high levels of glycine and tyrosine, compared to normal mice.
6 citations
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June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
1 citations
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August 2020 This study found that mutations affecting hair keratin expression on Chromosome 15 in mice may cause altered hair and skin features similar to other known mouse mutations.
February 1999 in “The anatomical record” This study observed defects in hair cuticle cross-linking in some, but not all, mouse mutants with sparse or structurally unsound hair.
April 1974 in “Pediatric Research” This study found that hair from mice with the Naked trait mutation has significantly lower levels of glycine and tyrosine, suggesting a deficiency in a specific protein fraction.
19 citations
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September 2021 in “British journal of dermatology/British journal of dermatology, Supplement” This study suggests that pretreatment with a PPAR-γ modulator may prevent damage to hair follicle stem cells caused by a chemotherapy metabolite, potentially offering a strategy to mitigate permanent chemotherapy-induced alopecia.
7 citations
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August 2020 in “Majalah Farmasetika” This review concluded that a herbal hair tonic formulated with 2.5% green tea leaf extract, in combination with specific solvents and additives, showed the best properties for stimulating hair growth.
January 2024 in “Veterinary Science and Medicine Journal” In this case report, a 1.5-year-old Pomeranian named Beb with respiratory and skin issues was diagnosed with pneumonia and demodecosis; following a two-week treatment including antibiotics, ivermectin, and supportive care, Beb's symptoms resolved, and hair regrowth was observed.
January 2024 in “Jurnal Ilmu Kesehatan Hewan” In this case report, a 7-month-old local dog named Oreo was diagnosed with demodicosis and helminthiasis and showed improvement in skin condition after 14 days of treatment with ivermectin, antihistamines, vitamin B complex, fish oil, and sulfur soap.
June 2022 in “Farmacevtičnij časopis” This study developed a technology for a combined gel named "Biosedum Plus" intended for treating and preventing radiation skin damage, detailing its formulation and critical processing parameters.
139 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.
10 citations
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January 2007 in “Dermatologic Surgery” This study reported that a new surgical technique resulted in minimal scars visible to the naked eye in most cases, suggesting a significant improvement over conventional closure techniques.
April 2025 in “Journal of Applied Veterinary Science And Technology” In this veterinary case report, the treatment of a 3-year-old male cat named Chipmunk for scabiosis, otitis externa, toxocariosis, and ancylostomiasis using ivermectin, diphenhydramine, drontal, and additional medications was found to be clinically effective.
September 2024 in “Journal of the American Academy of Dermatology” In this study, a novel compound named AH-001 demonstrated effective androgen receptor protein degradation, reducing hair loss progression in a mouse model of androgenetic alopecia, with minimal systemic exposure and side effects, suggesting potential for safer treatment.
August 2023 in “Clinical and Experimental Dermatology” The document discusses a special exam case for formulating and using systemic therapy named Athena.
May 2020 in “Business Innovation & Entrepreneurship Journal” This study discusses the development of a turmeric-based herbal hair removal product named PASIKULA, highlighting its potential to increase the economic value of turmeric and acceptance by consumers.
January 2007 in “Dermatologic Surgery” This study presents a new surgical technique that frequently results in minimal scars visible to the naked eye, marking a significant improvement over traditional methods.