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This study found that a newly identified gene, mK17n, may explain the lack of nail issues in mK17 null mice by compensating for mK17's function in the nail bed.

This study found that partial protein extraction from keratinized tissues, such as hair and nails, reveals protein patterns distinct from whole protein extracts, including the presence of ubiquitin.

This study found that trichocytic cytokeratins, typically found in hair, are also present in nails, filiform papillae of the tongue, and the epithelial reticulum of the thymus.

This study indicates that nail-matrical fibroblasts can induce hard keratin expression in non-nail-matrical keratinocytes, suggesting potential for using non-nail-matrical epidermal grafts to treat nail injuries.

The document concludes that skin and nail changes can indicate various underlying health conditions.

This study at B.J. Medical College and Civil Hospital highlighted an extensive range of nail disorders, with onychomycosis being the most common, and emphasized the importance of nails in diagnosing both dermatological and systemic conditions.

This review discusses the regeneration capabilities of various vertebrate tissues, focusing on the unique ability of certain species to regenerate teeth and lens, and reports no new results.

This study found that T cytokeratins appear more gradually and with complex coexpression patterns in developing nail structures compared to the more abrupt transition in hair follicles.

This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.

In this study of elderly patients at an Indian medical center, researchers found that xerosis was the most common physiological skin change and pruritus was the most frequent complaint.

This study highlights that smoker's mustache, a tobacco-related hair discoloration on the upper lip, is asymptomatic, generally unnoticed, and may resolve if smoking is discontinued, though patients often continue smoking.

This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

This review explores the biomechanical factors and signaling systems, like Wnt, involved in the pathophysiology of psoriatic nail lesions and reports no new results.

The Nd:YAG laser is a successful and safe way to treat ingrown and pincer nails.

This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.

In this study, oral acitretin therapy for psoriasis was associated with excess granulation tissue in the nail sulcus and noncicatricial universal alopecia.

This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.

In this study, Flii overexpression in mice enhanced fingertip regeneration and nail formation after both distal and proximal amputations, suggesting a role in digit and hair follicle regeneration possibly involving Wnt signaling.

This systematic review found that estrogen deficiency in postmenopausal women leads to structural and symptomatic changes in genital and cutaneous tissues, with local estrogen therapy providing short-term benefits, while evidence for device-based treatments remains limited and requires larger trials.

This study describes previously unknown immune characteristics of the normal human nail, highlighting its similarities to the hair follicle immune system and suggesting an immune privilege in the proximal nail matrix that both provides autoimmunity protection and presents infection susceptibility.

This study revealed that BMP5 in onychofibroblasts may play a key role in the differentiation of nail matrix keratinocytes, highlighting transcriptional similarities between nail and hair structures.

This study presented cases of severe and permanent nail changes resembling lichen planus in patients with chilblain lupus erythematosus, suggesting a unique pattern related to cold exposure rather than typical histopathology findings.

This study suggests that using stable isotope analysis on various tissues can effectively reconstruct individual life histories, providing insights into both the individual and broader population from the Romano-Christian period in Egypt.

This review discusses common hair and nail diseases in the elderly and reports no new clinical results, noting their significant impact on quality of life.

Cryotherapy is effective for ingrown toenails, especially in single cases, but has high recurrence in younger and bilateral cases.

This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.

This review discusses keratin disorders and potential RNA interference therapeutics, reporting no new clinical findings but highlighting the promise of siRNA for future treatments.

This article reviews the skin condition myxedema associated with hypothyroidism, highlighting its characteristic non-pitting, glycosaminoglycan-rich nature, and reports no new results.

This study successfully developed and characterized a monospecific monoclonal antibody, LHTric-1, that specifically localizes to the pre-cortical region of the hair follicle and can aid research on hair and nail formation.

This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.