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This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.

This article presents a case of a seventeen-year-old female with dermatopathia pigmentosa reticularis and emphasizes the importance of distinguishing its clinical features from other similar disorders, supported by dermoscopic and histopathological findings.

This article reviews the clinical aspects and potential mechanisms of chronic graft vs host disease skin manifestations, describing a novel form of premature skin aging, but presents no new research findings.

This study found that 76.19% of patients with acquired hypoparathyroidism had mucocutaneous manifestations, with common features including loss of hair and xerotic skin.

This case report describes a 56-year-old male with chronic watery diarrhea, hyperpigmentation, and alopecia, in whom colonoscopy revealed multiple polypoidal lesions from the distal transverse colon to the rectum.

This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.

Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.

This case report describes a patient with skin and nail hyperpigmentation and premature gray hair due to vitamin B12 deficiency, which were reversed after treatment with cyanocobalamin.

In this study, researchers at the Hospital Militar Universitario “Dr. Carlos Arvelo” found that among children under five with severe malnutrition, skin pigmentation changes and extreme thinness were the most common signs.

This study reported that among US Spanish speakers with limited English proficiency, online searches for dermatological information most frequently focused on "pigmentation/dark spots" and "hair loss," with "pigmentation/dark spots" being the most common search term from 2010 to 2020.

This study reports the first documented case of Cronkhite-Canada syndrome in a patient with myelodysplastic syndrome, where corticosteroids dramatically improved the patient's condition.

This study describes the diagnosis and successful management of Cronkhite-Canada syndrome in a 78-year-old man, highlighting improvement in symptoms and endoscopic findings after treatment with prednisone and supportive therapies.

This report documents a case of Cronkhite-Canada Syndrome in a 56-year-old Laotian man, who successfully improved with vitamin supplementation and medical treatment after experiencing weight loss, alopecia, and gastrointestinal polyposis.

This article reviews recent trends and developments in dermoscopy, highlighting its expanding use beyond pigmented lesions, and reports no new clinical results.

This review outlines how dermoscopy enhances diagnostic accuracy by up to 30% compared to unaided visual inspection and explores its potential as a research tool without presenting new research findings.

This article discusses various pruritic dermatoses that can occur during pregnancy, emphasizing the importance of physician skill in diagnosing and treating these conditions; it reports no new findings.

This letter to the editor discusses the natural course of epidermolysis bullosa simplex with mottled pigmentation in a Japanese family but does not present new clinical results.

This case report highlights a rare instance of fingernail and toenail hyperpigmentation following the use of valproic acid, which resolved after discontinuation of the drug.

This review discusses recent advances in the genetic understanding of inherited hair and nail disorders and reports no new clinical results.

This study reports previously unreported nail features in Cronkhite-Canada syndrome, specifically recurrent onychomadesis of all 20 nails linked to systemic illness.

A 73-year-old man's grey-white hair turned dark brown after eczema treatment.

Different nail disorders are treated by targeting their specific causes and using appropriate medications or protective measures.

This study found that nail abnormalities, particularly longitudinal ridging, were more frequent in vitiligo patients (78%) compared to healthy controls (55%).

This report details a case of hair, nail, and pigmentary disorders occurring 10 months after starting abemaciclib for metastatic breast cancer, highlighting that cutaneous side effects, although less frequent, can lead to discontinuation in 25% of cases.

This article reviews the structural similarities and common disorders of hair and nails, highlighting their joint involvement in congenital and acquired conditions, but it reports no new clinical results.

This study observed that 78.3% of patients with alopecia areata exhibited nail changes detectable by dermoscopy, notably nail pitting, in contrast to 14.2% of healthy controls, with these changes significantly associated with disease severity, age, and duration.

This study found that the oral supplement INVERSION® Femme significantly reduced weight and hair loss and improved skin and nails in overweight women.

This review discusses the effects of pregnancy on melanocytic nevi and reports no new clinical results; it suggests that changing nevi during pregnancy should be evaluated similarly to those in nonpregnant patients.

This study demonstrates that Rac1 activity is essential for normal hair follicle formation but influences hair structure and pigmentation, in terminal differentiation, through alterations in hair shaft, cuticle, and pigmentation organization.

This case report describes a 35-year-old woman with diffuse partial woolly hair occurring alongside epidermolysis bullosa with mottled pigmentation.