September 2024 in “Cureus” This case report outlines a 10-year-old boy who experienced a six-year history of twenty-nail dystrophy, highlighting the importance of physical examination for early diagnosis and management of nail disorders, with his primary symptoms involving nail disfigurement and alopecia areata, but no other health issues.
September 2023 in “Cureus” This study at B.J. Medical College and Civil Hospital highlighted an extensive range of nail disorders, with onychomycosis being the most common, and emphasized the importance of nails in diagnosing both dermatological and systemic conditions.
9 citations
,
April 2018 in “Journal of Dermatological Treatment” This study found that oral tofacitinib monotherapy improved nail changes in 73.3% of adults with moderate-to-severe alopecia areata over a median period of 5 months, but nail improvement was not linked to the severity of hair loss or hair regrowth.
8 citations
,
May 2021 in “Journal of the European Academy of Dermatology and Venereology” This case report describes a 23-year-old male patient with nail discoloration that may be associated with COVID-19, suggesting possible microvascular damage.
7 citations
,
December 2008 in “Expert Review of Dermatology” This article reviews hair and nail disorders in children, emphasizing their prevalence, congenital and acquired origins, and the diagnostic challenges compared to treatment, but reports no new clinical results.
3 citations
,
January 2019 in “Annals of dermatology/Annals of Dermatology” Hydroxychloroquine effectively treated twenty-nail dystrophy in a patient with alopecia areata.
1 citations
,
November 2025 in “Journal of Korean Medical Association” This review describes nail changes linked to various non-infectious skin diseases, highlighting how these alterations can help diagnose and manage conditions like psoriasis and lupus by noting specific and overlapping nail characteristics.
November 2018 in “The European research journal” In this study, researchers found that patients with alopecia areata who had nail involvement or a history of autoimmune disease showed significantly higher red cell distribution width levels.
January 2015 in “Dermatology online journal” This case report reviews a 67-year-old man with both alopecia totalis and lichen planus of the nails, suggesting a possible autoimmune link between these rare concurrent conditions, but presents no new clinical data.
This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal Algerian women.
This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal Algerian women, affecting nearly 60% of participants.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Topical spironolactone effectively treats hair loss in women.
January 2016 in “Dermatology Review” This review details various skin manifestations linked to different endocrine disorders but does not report any new clinical results.
7 citations
,
January 2017 in “Annals of Dermatology” This study found that among patients with twenty-nail dystrophy, those treated with oral cyclosporine in combination with a dietary supplement showed significantly better improvement in nail condition and quality of life than those treated with the supplement alone.
April 2019 in “International journal of research in dermatology” This case report describes a 6-year-old child with twenty nail dystrophy and alopecia areata of the scalp.
7 citations
,
May 2014 in “Clinical practice” This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.
July 2018 in “British Journal of Dermatology” Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.
December 2022 in “Journal of medical sciences and health” This study found that histomorphological evaluation of nail punch biopsies is useful for diagnosing various nail-related dermatoses, with psoriasis being the most common condition observed.
1 citations
,
July 2016 in “British Journal of Dermatology” Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.
7 citations
,
June 2015 in “Cutaneous and Ocular Toxicology” This study attempts to classify histomorphologic reactions to drugs to aid in diagnosing drug eruptions, which are common in hospitalized patients but lack specific diagnostic features.
1 citations
,
October 2019 in “International journal of contemporary pediatrics” This case report highlights a 12-year-old boy with twenty nail dystrophy in isolation, emphasizing the need for thorough physical exams to distinguish nail disorders and provide appropriate management and counseling on the condition's benign nature and good prognosis.
26 citations
,
October 2016 in “Case Reports in Dermatology” In this study, tofacitinib treatment in a male patient with alopecia areata led to significant hair regrowth and improvement in nail dystrophy symptoms, restoring finger function within 10 months.
14 citations
,
November 1963 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews the identification and characterization of soluble proteins in horny tissues such as calluses and psoriatic scales, but reports no new clinical results.
8 citations
,
April 2017 in “International Journal of Dermatology” This study found that applying 5% topical minoxidil twice daily significantly increased nail growth rate in healthy participants compared to untreated nails, with effects observable from the first week.
July 2017 in “British Journal of Dermatology” The document concludes that scalp conditions have various causes and can present in many different ways.
80 citations
,
June 2020 in “Dermatopathology” This review discusses the various skin lesions associated with COVID-19, which vary in type and severity, and reports that these lesions can appear before other symptoms and typically resolve spontaneously.
30 citations
,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the effects of thyroid hormone on the skin and explores the potential for using it to treat skin diseases, but reports no new clinical results.
64 citations
,
June 1992 in “International Journal of Dermatology” Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
21 citations
,
January 2013 in “Clinical Endoscopy” This study reports the first case in South Korea of Cronkhite-Canada syndrome associated with malignant colon polyp and serrated adenoma.
21 citations
,
October 1980 in “Gastroenterology” This report is the first to associate Cronkhite-Canada syndrome with multiple myeloma, describing regenerative pseudopolyps in a 58-year-old woman rather than true adenomatous polyps.