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Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

PAI-2 helps in the maturation and protection of hair and nail cells.

Transglutaminase activity is important for skin and is found in both mammals and birds.

Tofacitinib citrate improved nail dystrophy and pain in patients with alopecia universalis without causing side effects.

Tofacitinib improves nail conditions in patients with severe hair loss and does not affect hair regrowth.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

Early intervention and tailored management can reduce skin side effects from cancer treatments.

Lab-grown nail cells show characteristics similar to natural nail and hair.

A man with total hair loss also developed a rare nail condition, likely due to autoimmune issues.

Activating β-catenin in certain skin cells speeds up hair growth in mice.

SGK3 is essential for proper hair growth and health.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Hydroxychloroquine effectively treated twenty-nail dystrophy in a patient with alopecia areata.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Lupus can cause hair loss and nail changes, with treatments available for both.