4 citations
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March 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
October 2019 in “UNESP Institutional Repository (São Paulo State University)” In this quasi-experimental clinical trial, researchers observed that topical minoxidil increased nail growth speed more than oral biotin in healthy adults, although combining them had no added benefit over minoxidil alone.
May 2021 in “Research journal of topical and cosmetic sciences” In this study, oral supplementation of Microcore’s TrichovitalsTM significantly improved the appearance of facial skin, hair, and nails over 12 weeks in healthy middle-aged adults compared to a control group.
This systematic review found that topical minoxidil significantly increases nail growth in healthy individuals and patients with nail disorders, showing a promising mean increase in growth rate and clinical response compared to controls, without serious adverse effects reported.
July 2025 in “Cosmoderma” In this study, a 90-day course of a plant-based supplement significantly improved hair density, skin hydration, and nail growth among participants with dermatological concerns, while also reducing hair fall and pigmentation, without adverse effects.
8 citations
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April 2017 in “International Journal of Dermatology” This study found that applying 5% topical minoxidil twice daily significantly increased nail growth rate in healthy participants compared to untreated nails, with effects observable from the first week.
April 2023 in “Asian Medical Journal and Alternative Medicine” This study found that applying 2% topical minoxidil resulted in a greater nail growth rate compared to 5% minoxidil and placebo over eight weeks, with no observed side effects, suggesting 2% is an effective concentration for accelerating nail growth.
December 2021 in “Trichology and cosmetology:” This study demonstrated that a daily oral supplement of 1000 mg Kera-Diet® improved hair and nail conditions in women experiencing acute telogen effluvium and brittle nail syndrome over three months.
January 2019 in “Journal of cosmetology & trichology” In this study, researchers found that supplementation with L-cystine, either alone or with a keratin hydrolysate, significantly improved hair density, hair and nail brightness, and nail growth in women experiencing acute telogen effluvium and brittle nail syndrome over three months.
July 2023 in “UNESP Institutional Repository (São Paulo State University)” This study found that oral minoxidil increased the growth rates of nails and hair in healthy adult men, with 2.5mg proving more effective for nails than 1mg, and both doses boosting hair growth, without significant adverse effects.
December 2024 in “European Journal of Dermatology” In this study, oral minoxidil treatment at 2.5 mg/day significantly increased nail growth speed by 50.7% and hair growth speed by 35.9% in healthy adult men, while also increasing heart rate but not affecting blood pressure.
In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
September 2023 in “Journal of Cosmetic Dermatology” This study concluded that topical minoxidil could effectively accelerate nail growth in both healthy individuals and those with nail disorders, though the regimen might differ across these groups.
February 2026 in “Journal of Clinical Medicine” In this narrative review, researchers found preliminary evidence suggesting that minoxidil, both topical and oral, may enhance nail growth and improve nail strength and appearance, though more extensive studies are needed to confirm its efficacy and safety for this off-label use.
13 citations
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November 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that topical clobetasol propionate cream provided a modest improvement in hair regrowth for alopecia areata patients, though those with atopy had higher relapse rates after treatment completion.
22 citations
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June 2001 in “International Journal of Cosmetic Science” This review discusses the role of iron from cosmetic sources in skin nutrition and reports no clinical results, highlighting its significance for skin, hair, and nail health.
13 citations
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August 1982 in “Archives of dermatology” This case report describes a 62-year-old man with psoriasis who developed a unique nail abnormality after two months of treatment with the oral retinoid etretinate, alongside hair thinning and cheilitis.
2 citations
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October 2016 This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.
January 2026 in “http://isrctn.com/” The food supplement may help reduce hair shedding and improve hair growth.
September 2016 in “Journal of dermatological science” This study found that COL17 plays a key role in regulating epidermal keratinocyte differentiation and proliferation, influencing the expression of differentiation markers and cellular growth in specific conditions.
February 2010 in “Journal of The American Academy of Dermatology” This study found that NB-002 demonstrated clear antifungal activity and clinically significant nail clearing in subjects with distal subungual onychomycosis and ≤50% nail involvement, compared to a vehicle treatment.
July 1980 in “Journal of The American Academy of Dermatology” The conference concluded that understanding hair and nail disorders is important, iron deficiency may be linked to hair loss, and while some treatments for skin conditions are effective, they may have risks and high costs.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.
March 2025 in “Dermatology” Systemic therapies improve nail psoriasis but have high side effects; more research is needed.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Old people's nails often have problems due to body changes, more diseases, and self-care difficulties, affecting their movement and hand use.
11 citations
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November 2005 in “The Journal of Dermatology” This report presents a unique case where a man developed Beau's lines on all fingers of one hand after a thumb injury, with the lines eventually disappearing as the nails grew.
June 2021 in “Current developments in nutrition” In this open-label study, participants reported that the LustrivaTM BH-002 two-step system improved various aspects of hair, skin, and nail health and appearance after three months of use.
March 2014 in “Journal of The American Academy of Dermatology” Terbinafine 250 mg is the most effective treatment for fungal nail infections.
February 2010 in “Journal of The American Academy of Dermatology” NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.
42 citations
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December 2019 in “Steroids” In this study, researchers developed a method to measure steroid hormones in hair and found that body hair typically contains higher levels of cortisone and testosterone compared to scalp hair, but hair pigmentation did not affect hormone concentrations significantly.