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Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.

Alopecia areata causes sudden hair loss, often on the scalp, and can be severe, especially with early onset or related health issues.

A child with ectodermal dysplasia-syndactyly syndrome has a new mutation in the NECTIN4 gene.

A boy with Pachyonychia congenita has a confirmed gene mutation, highlighting the need for a local genetic database in India.

Zinc is important for health and its supplementation may help treat various conditions.

A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.

Biotin is important for health, but taking extra usually doesn't help unless you're deficient.

Most patients with chronic kidney disease had skin issues like paleness and dry skin, and treating these can improve their lives.

Valproic acid can cause dark lines on nails.

Higher IL-17A levels indicate more severe alopecia areata.

Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.

Clouston's syndrome is a rare disorder affecting nails, hair, teeth, and skin, caused by a gene mutation, and currently has no treatment, only supportive care.

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

Small bowel lesions in Cronkhite-Canada syndrome persist despite steroid treatment.

Smoking and certain health conditions like thyroid disease may make palmoplantar pustulosis harder to treat.

New RIPK4 gene mutations were found to cause a type of skin and limb birth defect.

Daclizumab may cause psoriasis-like skin problems in multiple sclerosis patients.

Intralesional steroids are the most effective treatment for alopecia areata.

Hair loss in young adults is common and varies in pattern, cause, and type.

Children with different rheumatologic diseases have specific skin symptoms that can help with diagnosis.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

About 22% of cancer patients had skin-related side effects from chemotherapy, but these were usually not severe enough to halt treatment.

A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.

The document explains various skin conditions and their treatments.

Skin problems are common in thyroid disorders, with dry skin in hypothyroidism and warm, soft skin in hyperthyroidism.

People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.

After chemotherapy for early breast cancer, 33.4% of patients had long-term significant hair loss, with some hair regrowth over time, but treatments for hair loss were largely ineffective.

Laser treatment is safe and can effectively treat toenail fungus, especially when combined with other treatments if no improvement is seen after about a year.

The Nd:YAG laser is a successful and safe way to treat ingrown and pincer nails.

The patient's hair loss is most likely due to diffuse alopecia areata.