129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
36 citations,
June 2018 in “Journal of The American Academy of Dermatology” Dermoscopy is useful for diagnosing various skin, hair, and nail disorders and can reduce the need for biopsies.
30 citations,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.
16 citations,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Children with HIV often have skin problems that can indicate the severity of their immune system damage.
14 citations,
April 2014 in “Medical Clinics of North America” The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
7 citations,
October 2020 in “Dermatology practical & conceptual” Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.
November 2013 in “International Journal of Medical and Health Sciences” Doctors often miss Hair Tourniquet Syndrome, which can lead to serious damage if not treated quickly.
62 citations,
October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
44 citations,
January 2005 in “Dermatology” Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.
January 2024 in “Archives of pharmacy practice” The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.
September 1983 in “Journal of The American Academy of Dermatology” Experts discussed hair care, genetic hair defects, hair loss treatments, nail surgery, lupus treatments, skin infections, and cosmetic allergies.
7 citations,
July 2019 in “Advances in preventive medicine” Most diabetic patients have skin problems, which are more common with longer diabetes duration and poor blood sugar control.
3 citations,
January 2018 in “Skin Appendage Disorders” Nail issues are common in alopecia areata patients.
208 citations,
July 2001 in “Journal of The American Academy of Dermatology” Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
101 citations,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
100 citations,
September 2016 in “Clinical transplantation/Clinical transplantation.” Voriconazole can cause serious side effects, especially in long-term use.
78 citations,
December 2011 in “Clinical toxicology” Excessive selenium from a supplement caused toxicity but patients recovered with care.
73 citations,
October 2013 in “International Journal of Cosmetic Science” Chemical hair straightening can damage hair and health, needing safer alternatives and stricter regulations.
61 citations,
October 2010 in “Postgraduate Medical Journal” Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.
42 citations,
April 2008 in “Acta materialia” Different ethnicities and treatments affect human hair strength and structure.
37 citations,
March 1990 in “The Journal of Pediatrics” Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
34 citations,
July 1987 in “The Journal of dermatologic surgery and oncology” Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.
32 citations,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
26 citations,
June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
22 citations,
November 2014 in “Psychiatric Clinics of North America” Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.
21 citations,
June 1990 in “British Journal of Dermatology” Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
19 citations,
May 1984 in “Digestive diseases and sciences” A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
17 citations,
July 2014 in “Our Dermatology Online” Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.
17 citations,
December 2002 in “Biochemical and biophysical research communications” Scientists found out how a specific protein in human hair cuticles behaves and is structured.
11 citations,
January 2017 in “Dermato-endocrinology” Skin and nail problems like hair loss, dry skin, and fungal infections are common in people with long-term Type 2 Diabetes and can be prevented with good blood sugar control and foot care.