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Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.

A 27-year-old with APS-1 showed improvement in symptoms after treatment.

Elderly in South India commonly suffer from skin issues like wrinkles, dryness, and infections, needing better skin care education.

A Jordanian family with Clouston syndrome has a common GJB6 gene mutation.

Baricitinib was effective and safe for severe hair loss treatment over 6 months.

Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.

A child with ectodermal dysplasia-syndactyly syndrome has a new mutation in the NECTIN4 gene.

A boy with Pachyonychia congenita has a confirmed gene mutation, highlighting the need for a local genetic database in India.

Clouston syndrome is inherited in an autosomal dominant pattern and caused by a specific gene mutation, with no current treatment available.

Most patients with chronic kidney disease had skin issues like paleness and dry skin, and treating these can improve their lives.

Clouston's syndrome is a rare disorder affecting nails, hair, teeth, and skin, caused by a gene mutation, and currently has no treatment, only supportive care.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.

People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.

After chemotherapy for early breast cancer, 33.4% of patients had long-term significant hair loss, with some hair regrowth over time, but treatments for hair loss were largely ineffective.

A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.

The conclusion is that proper recognition and treatment of skin conditions are crucial for the elderly due to changes in skin, nails, and hair with age, and the impact of these conditions on health and mobility.

New treatments targeting specific genes show promise for treating keratin disorders.

Platelet-rich plasma (PRP) is effective in treating various skin conditions and improving hair density, thickness, and patient satisfaction, with lower relapse rates for Alopecia Areata.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

Six genetic conditions are often linked to complete scalp hair loss in children.

Cortisone and ACTH didn't help her hair or nails, but her hair grew back on its own.

The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.

Etanercept improved symptoms of a specific type of psoriatic arthritis in a patient who didn't respond to other treatments.

Acitretin can cause excess tissue growth and hair loss.

Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.

Vegan collagen builder improves hair growth, skin smoothness, and reduces wrinkles and pain.

Nutricosmetics for hair treatment often contain biotin, pyridoxine, zinc, and other nutrients, but more research and professional guidance are needed for their use.

A boy's hair, nails, and skin improved after 6 months of steroid treatment.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.