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In this study, a water-soluble nail strengthener containing Pistacia lentiscus and hyaluronic acid significantly improved the appearance and firmness of brittle nails in both in vitro and clinical settings.

This multicenter study found that hair and nail disorders, particularly telogen effluvium, commonly developed in patients after severe COVID-19 infection.

In this retrospective study, the authors explored the use of minoxidil and vitamin E for treating nail growth disorders, but no specific outcomes or results are reported in the abstract.

This systematic review found that topical 5% minoxidil significantly increased nail growth in healthy individuals after one month, and showed an 81% clinical response in onychomadesis patients after 12 months, without serious adverse effects, although more extensive trials are needed to confirm long-term outcomes.

This review discusses how emerging technologies in dermatology are enhancing the ability to diagnose and treat hair and nail disorders more accurately and effectively, highlighting advancements in both diagnostic techniques and therapeutic methods such as AI-driven technologies that personalize patient care and improve outcomes.

This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.

This study found that Cynatine HNS significantly improved hair and nail health in women after 90 days compared to placebo.

This study found that hospitalized pediatric COVID-19 patients frequently display skin, mucosal, and nail manifestations, particularly periorbital erythema and edema, and the authors suggest COVID-19 be considered among childhood viral exanthem rashes.

This study found that a combination of cantigi and henna leaf extracts, in a 1:2 ratio, demonstrated the strongest antioxidant activity with an IC50 value of 29.85 µg/mL.

Natural and holistic treatments offer alternative options for nail psoriasis and hair loss.

In this study, dermatologists from the Spanish Hair and Nail Disorders Group viewed post-finasteride syndrome as rare and primarily of psychiatric origin, with limited scientific evidence supporting its existence.

This research explores the potential of the metaverse for transforming dermatology, particularly in treating hair and nail disorders through virtual consultations and support communities, but highlights significant challenges such as technological limitations, accessibility for underserved populations, and the need for empirical validation.

This study found that protective measures against COVID-19, such as prolonged mask-wearing and frequent hand washing, were associated with skin issues, hair loss, and nail brittleness among participants in Iraq.

This study identified a homozygous missense mutation in the KRTHB5 gene linked to pure hair–nail ectodermal dysplasias in a large consanguineous Pakistani family, providing new insights into the condition's molecular pathogenesis.

This response article concurs with Dr. Lipner's critique that biotin supplementation is largely unsupported for routine use in dermatological conditions, with evidence mostly limited to case reports.

This study identified nine compounds that activate Wnt signaling, with aminoacridine and proflavine especially promoting hair and nail regeneration in mouse models, highlighting new therapeutic candidates from existing FDA-approved and natural compounds.

In this quasi-experimental clinical trial, researchers observed that topical minoxidil increased nail growth speed more than oral biotin in healthy adults, although combining them had no added benefit over minoxidil alone.

This study found that MAP-2 is intensely expressed in the companion layer of the hair follicle, suggesting its potential importance to follicle integrity and possible involvement in some types of alopecia.

This review discusses the potential risks associated with skin, hair, and nail supplements, highlighting concerns about safety, efficacy, and lack of regulation but reports no new clinical results.

This article outlines methods to study the skin and its molecular traits, focusing on interpretation and techniques applicable to mouse models, including diverse assays and approaches like electron microscopy and large-scale lipid analyses.

In this animal study, applying a combination of inositol-stabilized arginine silicate complex and magnesium biotinate promoted hair growth but not nail growth.

This study examined Instagram posts advertising dermatological supplements and found many lacked detailed ingredient information and made unverified health claims, potentially influencing consumer trust and highlighting the need for dermatologist engagement on social media.

In this study, researchers identified nine FDA-approved drugs that activate the Wnt signaling pathway, with Aminoacridine, especially when combined with Minoxidil, showing promising effects on hair and nail growth in mice, suggesting potential treatments for hair and nail loss pending further clinical trials.

This review discusses the evidence for biotin supplementation in treating hair loss, concluding that its benefits are poorly supported by data and advising against routine use without more compelling future trials.