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Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Male pattern baldness involves genetics, hormones, and needs better treatments.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.