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Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.

CCDC22 and CCDC93 are essential for root and root hair growth in Arabidopsis.

Skin may help in getting rid of excess iron through the process of skin cell renewal.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Genetic defects and UV radiation cause skin damage and aging.

Chemical treatments damage hair more than UV exposure, making it thinner and less flexible.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.