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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

The most effective treatments for hair loss are minoxidil, finasteride, PRP, and hair transplants, with steroids and immunosuppressants for autoimmune types.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Polymeric nanoparticles show promise for treating skin diseases.

PGD2 stops hair growth and is higher in bald men with AGA.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Minoxidil boosts hair growth by activating PGHS-1.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.