Researchers made new compounds that could potentially be developed into anticancer drugs.
March 2024 in “Journal of biobased materials and bioenergy” Tea tree oil may help treat scalp alopecia by promoting hair follicle stem cell growth.
January 2024 in “Biochemical and Biophysical Research Communications” Lack of zinc can cause hearing loss by damaging important parts of inner ear cells in mice.
December 2021 in “Jurnal ilmiah Manuntung” The best hair growth results were achieved with a hair tonic containing 5% gotu kola extract and 0.04% garlic extract.
1 citations,
April 2007 in “Journal of Korean Medicine Rehabilitation” Saengbal-eum may help hair grow on mice with removed hair.
February 2004 in “The New England Journal of Medicine” The book is a comprehensive and current guide on hair disorders, with minor flaws.
26 citations,
January 1992 in “Cancer investigation” N-acetylcysteine and ImuVert can prevent hair loss in rats caused by chemotherapy.
24 citations,
June 2020 in “Dermatologic Therapy” New drugs like N-acetylcysteine and dronabinol show promise for treating hair-pulling disorder.
24 citations,
May 2006 in “Proceedings of the National Academy of Sciences of the United States of America” Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.
18 citations,
April 2001 in “Bioorganic & Medicinal Chemistry Letters” The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
14 citations,
February 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Trichotillomania is often misdiagnosed as alopecia areata and can be treated effectively with N-acetylcysteine and psychotropic drugs.
14 citations,
January 2004 in “Journal of Biochemical and Molecular Toxicology” Mustard gas exposure causes hair loss, but treating with N-acetylcysteine can prevent it.
9 citations,
October 2008 in “Mutation research” N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
8 citations,
January 2011 in “Organic and Biomolecular Chemistry” Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.
4 citations,
October 2023 in “Dermatology” The best treatment for lichen planopilaris is a combination of clobetasol, hydroxychloroquine, and N-acetylcysteine.
3 citations,
November 2018 in “Journal of cellular physiology” Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.
3 citations,
April 2011 in “Neuropsychiatry” Behavioral therapy, N-acetyl cysteine, and olanzapine may help treat trichotillomania.
November 2024 in “Actas Dermo-Sifiliográficas” N-acetylcysteine and memantine are recommended as safe and effective treatments for trichotillomania.
January 2023 in “Figshare” Triple therapy with clobetasol, hydroxychloroquine, and N-acetylcysteine is recommended for better outcomes in treating lichen planopilaris.
January 2024 in “International Journal of Cosmetic Science” A new method using 1,4-n-butylene dimaleate effectively repairs and strengthens damaged hair.
April 1974 in “Pediatric Research” The Naked (N) trait in mice is linked to lower glycine and tyrosine in hair proteins.
October 2005 in “Nature reviews. Molecular cell biology (Print)” Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
249 citations,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
215 citations,
March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
89 citations,
February 1993 in “Journal of Medicinal Chemistry” New compounds called benzoquinolinones may treat conditions linked to excess DHT.
84 citations,
July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
75 citations,
March 2018 in “Molecules/Molecules online/Molecules annual” L-Cysteine may have health benefits, but its effectiveness is still debated due to limited clinical trial data.
70 citations,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
69 citations,
September 1991 in “Journal of Surgical Research” Understanding how fetal wounds heal could help improve healing in adults.
68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.