21 citations
,
April 1982 in “Genetics Research” In this study, researchers observed that mice with the naked gene showed frequent absence of hair cuticle and cortical cells during follicle growth, with abnormal keratin deposition also noted.
1 citations
,
May 2022 in “Research Square (Research Square)” The study demonstrates that acetate treatment may alleviate PCOS-associated depression in rats by reducing neuroinflammation and modifying epigenetic changes in the brain.
68 citations
,
September 1990 in “Biochemical Pharmacology” This study found that minoxidil is bioactivated through sulfation by the phenol-sulfating form of phenol sulfotransferase in human liver.
56 citations
,
September 2013 in “Journal of Biochemistry and Molecular Biology” This study observed that androgen treatment increased ROS production and TGF-β1 secretion in rat hair follicle dermal papilla cells, suggesting that the androgen-induced TGF-β1 is mediated by ROS.
7 citations
,
January 1991 in “Comparative biochemistry and physiology. A. Comparative physiology” This study found that a dietary change in common marmosets significantly reduced in vitro erythrocyte haemolysis, improved skin lesions, and promoted complete fur regrowth, possibly due to increased vitamin E levels.
4 citations
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August 2021 in “Theriogenology” This study found that blocking neurosteroid synthesis in pregnant sheep increased HPA axis activity, particularly under stress, suggesting neurosteroids help modulate stress response.
3 citations
,
October 2019 in “EMBO molecular medicine” This study reports that the nuclear receptor co-repressor 1 (NCoR1) inhibits cardiac hypertrophy by stabilizing the MEF2 and class II HDACs complex, potentially offering a target for new therapies.
2 citations
,
August 2023 in “Development” In this study, researchers explored how hair follicle orientation is affected in the rosette fancy mouse and found that a mutation in the PCP gene Fzd6 caused reversed hair orientations in the posterior region, leading to the formation of unique whorls.
2 citations
,
December 2024 in “Microscopy Research and Technique” This study introduced a novel microscopy system using an Er3 + −doped femtosecond fiber laser, achieving detailed imaging of biological structures in plant and skin samples with improved spatial resolution for various applications, including in vivo imaging.
1 citations
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July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” This study found that rubbing significantly increased skin permeation of caffeine but not rhododendrol, with the direction of rubbing playing a crucial role in caffeine's enhancement.
April 2017 in “Journal of Pharmaceutical Investigation” In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.
33 citations
,
January 2001 in “Critical care clinics” This article reviews the roles and synthesis of essential long-chain fatty acids in the body and reports no new research findings; it emphasizes the importance of dietary sources for these lipids.
26 citations
,
February 2020 in “Frontiers in genetics” This study identified three candidate genes (CORT, FGF5, and CD36) associated with cold climate adaptation in Yanbian cattle through genome resequencing and comparison with African tropical cattle.
4 citations
,
January 1997 in “EXPERIMENTAL ANIMALS” This study suggests that increased activity of the histamine synthesizing enzyme histidine decarboxylase may play a role in initiating the anagen phase of hair regrowth in mice.
2 citations
,
March 2018 in “ACS Sustainable Chemistry & Engineering” This study found that stepwise thermal treatment of human hair waste at temperatures from 200 to 450 °C produced hollow microtubes, with structure changes influenced by temperature, core degradation, and cortex melting.
August 2019 in “Journal of The American Academy of Dermatology” No link found between hair loss severity and PSA levels in men.
January 2014 in “Genes and Cells” This study found that transplanting human cord blood mononuclear cells transfected with a plasmid encoding VEGF and FGF2 into rat skin wounds may accelerate the wound healing process.
14 citations
,
December 1991 in “Annals of the New York Academy of Sciences” This study reports that lower levels of N-myc mRNA are observed when hair growth ceases in certain phases in mice, and attempts to create transgenic mice for further investigation resulted in high embryonic mortality.
59 citations
,
November 2018 in “Psychoneuroendocrinology” This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.
This scoping review identifies various pharmacological agents and five key mechanistic strategies being studied in vivo to mitigate multi-organ toxicity caused by cytarabine, with apraglutide and N-acetylcysteine highlighted as promising candidates for clinical application.
January 2021 in “Advanced Biomedical Engineering” This study found that hair implant needles with longer point lengths and smaller bevel angles required less total work for insertion, which corresponded with surgeons' perceptions of insertion force differences.
12 citations
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August 1984 in “Genetics Research” In this study, researchers found that the naked (N) gene in mice indirectly affects the synthesis of structural proteins in mouse hair, resulting in reduced high tyrosine protein content and unusual amino acid compositions.
March 2022 in “IP Indian journal of clinical and experimental dermatology” This study found that ferritin and cobalamin levels were better indicators than hemoglobin in assessing chronic nonscarring hair loss in females of reproductive age.
22 citations
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February 2013 in “Wound Repair and Regeneration” In this study, CD109 overexpression in transgenic mice led to reduced inflammation and improved collagen organization during wound healing without affecting wound closure.
August 2017 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” In this study, melatonin supplementation in cattle during mid to late gestation decreased the temperature of unshaved skin areas but did not affect rectal temperature or body weight.
13 citations
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June 2016 in “Dermatologic Therapy” This study found that minoxidil applied to a damp scalp may increase drug penetration in vitro, potentially improving treatment effectiveness.
15 citations
,
March 1987 in “Phycologia” This study found that phosphorus limitation in Chaetophorales strains led to enhanced hair formation and increased phosphatase activity, suggesting a significant relationship between phosphorus status and morphology.
5 citations
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March 2009 in “Skin Pharmacology and Physiology” This study found that DNA flow cytometry effectively evaluates physiological and hormonal influences on cell cycle kinetics of human anagen hair bulbs, with increased S phase cells observed in male pattern baldness, hirsutism, and hyperthyroidism.
1 citations
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October 2023 in “PloS one” This study found that testosterone concentrations in hair samples were moderately stable over three months, with cosmetic treatments like coloring increasing testosterone levels, while natural hair color in untreated hair did not affect testosterone measurements.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that patients with isolated neutropenia exhibit significant differences in certain lymphocyte and monocyte subtypes compared to healthy controls, including higher neutrophil/lymphocyte MFI ratios and lower percentages of natural killer cells.