research Tumor Mapping in Two Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
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research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
research Clinical Efficacy and Safety of Low-Dose Flutamide Alone and Combined with an Oral Contraceptive for the Treatment of Idiopathic Hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research CD98hc (SLC3A2) Regulation of Skin Homeostasis Wanes With Age
CD98hc's role in skin health decreases with age.
research Skin Diseases in Pregnancy
Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.
research Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients
Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.
research Polycystic Ovary Syndrome: A Review for Dermatologists
A team approach is crucial for managing PCOS, with dermatologists playing a key role.
research Controlling the Stem Cell Niche: Right Time, Right Place, Right Strength
Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
research Bone Density Is Normal in Male Rats Treated with Finasteride
Finasteride doesn't affect bone density in male rats.
research Contact Allergy to Essential Oils Cannot Always Be Predicted from Allergy to Fragrance Markers in the Baseline Series
Allergies to some essential oils may not be found with standard fragrance tests.
research Identifying the Supportive Care Needs of Men and Women Affected by Chemotherapy-Induced Alopecia: A Systematic Review
People undergoing chemotherapy need better support and information to cope with hair loss.
research Infertility and Teratogenicity After Paternal Exposure to Systemic Dermatologic Medications: A Systematic Review
Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.
research Follicular Dysplasia in Five Weimaraners
Five Weimaraners had a milder form of color dilution alopecia causing hair loss and skin issues.
research Hair Follicle Regeneration Suppresses Ras-Driven Oncogenic Growth
Hair follicle regeneration may slow tumor growth.
research FCE 28260, A New 5α-Reductase Inhibitor: In Vitro and In Vivo Effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects Against Malignant Progression
Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.
research Oral Vitamin A as an Adjunct Treatment for Canine Sebaceous Adenitis
Vitamin A might be a safe extra treatment for dogs with sebaceous adenitis, but more research is needed to prove its effectiveness.
research Adam10 Haploinsufficiency Causes Freckle-Like Macules in Hairless Mice
A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research The Current State of Play in the Histopathologic Assessment of Alopecia: Two for One or One for Two?
The document concludes that choosing the right biopsy site is crucial for accurate alopecia diagnosis, and combining methods can improve results.
research Sexual Dysfunction in Men Taking Systemic Dermatologic Medication: A Systematic Review
Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.
research Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts
The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
research 4-(Alkylthio)- and 4-(Arylthio)-Benzonitrile Derivatives as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
research Preparation of 4-Aryl-2-Trifluoromethylbenzonitrile Derivatives as Androgen Receptor Antagonists for Topical Suppression of Sebum Production
Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
research Changes in Serum Free Testosterone, Sleep Patterns, and 5-Alpha-Reductase Type I Activity Influence Sebum Excretion in Female Subjects
Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.
research Receipt of 5-Alpha Reductase Inhibitors Before Radical Cystectomy: Do They Render High-Grade Bladder Tumors Less Aggressive?
Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.
research Cutaneous Crohn's Disease Treated with Infliximab and 4 Years of Follow-Up
Infliximab improved skin and bowel symptoms in Crohn's disease but caused side effects and the disease returned after stopping treatment.
research Alopecia Areata Incognita in Cronkhite-Canada Syndrome
The report suggests that hair loss in Cronkhite-Canada syndrome may be caused by alopecia areata incognita, as shown by a patient's improvement with treatment.
research Diphenyl Ethers as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
research Bone Density Is Normal in Male Rats Treated with Finasteride
Finasteride doesn't affect bone density in male rats.
research Revisiting the Significance of Keratin Expression in Complex Epithelia
Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.