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Systemic diseases can cause hair loss, which is often reversible with treatment.

Histone modification is key in treating chronic inflammatory skin diseases.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

High doses of tryptophan may cause eosinophilic fasciitis.

Plant-based products can improve hair and skin health without harmful side effects.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Buxus wallichiana extract improves hair growth and has antioxidant properties, with oral use more effective than topical.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Some medications might contribute to male infertility, with finasteride showing a high number of reports.

Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Spanlastic-laden nanogel could be a better way to deliver hair growth medication through the skin for treating hair loss.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Hairless protein can block vitamin D activation in skin cells.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Microneedling improves skin and hair conditions by enhancing treatment absorption and stimulating growth factors.

Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.

Breast cancer may be detectable through changes in scalp hair lipids.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

The PRP-like cosmetic with biomimetic peptides is potentially effective and safe for treating alopecia areata.