research Quantification of Squalene and Lactic Acid in Hair Bulbs with Damaged Sheaths: Are They Metabolic Wastes in Alopecia?
Squalene may be a marker for certain types of alopecia.
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research ROBO4 Deletion Ameliorates PAF-Mediated Skin Inflammation by Regulating the mRNA Translation Efficiency of LPCAT1/LPCAT2 and the Expression of PAF Receptor
Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
research The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes Through the β-Arrestin Pathway
Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.
research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant
Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
research The Role of EAAT4 in Epidermal Differentiation and Calcium Homeostasis During Aging
EAAT4 decreases with age, harming skin function and calcium balance.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
research Exploring Phytotherapy for Alopecia: Efficacy, Mechanisms, and Future Directions
Herbal remedies might help with hair loss but need more research for safety and effectiveness.
research Potential Role and Therapeutic Interests of Myo-Inositol in Metabolic Diseases
Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
research Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development
Ozone therapy might improve cancer treatment and reduce its side effects.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Skin-Specific Regulation of SREBP Processing and Lipid Biosynthesis by Glycerol Kinase 5
A gene called Gk5 controls lipid production in the skin and affects hair growth.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research The Multiple Uses of Azelaic Acid in Dermatology: Mechanism of Action, Preparations, and Potential Therapeutic Applications
Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
research Biotin Is Required for Zinc Homeostasis in the Skin
Biotin is important for keeping zinc levels balanced in the skin and its lack can cause hair loss.
research Synergistic Phytochemical and Pharmacological Actions of Hair Rise Microemulsion: A Novel Herbal Formulation for Androgenetic Alopecia and Hair Growth Stimulation
Hair RiseTM microemulsion effectively promotes hair growth and treats hair loss better than standard treatments.
research Biotin And Biotinidase Deficiency
Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
research The Acyl-CoA Binding Protein Is Required For Normal Epidermal Barrier Function In Mice
ACBP is crucial for healthy skin in mice.
research Epigenetic Regulation in Adult Stem Cells and Cancers
Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
research Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model
The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
research Monocyclic Aromatic Compounds: Synthesis and Biological Activities
Monocyclic aromatic compounds are important for developing various drugs and treatments.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Pre-Receptor Regulation of the Androgen Receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer
A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.
research Cuscuta Reflexa (Dodder Plant): A Critical Review on the Medicinal Plant Used in Ayurveda
The dodder plant has anti-inflammatory, antimicrobial properties, and may promote hair growth.
research Ethnopharmacological Significance of Eclipta Alba (L.) Hassk. (Asteraceae)
Eclipta alba has many health benefits and contains compounds with potential for drug development.
research Progesterone Enhances Ethanol-Induced Modulation of Mesocortical Dopamine Neurons: Antagonism by Finasteride
Progesterone boosts alcohol's effect on brain, finasteride counters it.