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    Glossary Myxedema

    severe hypothyroidism causing skin and tissue swelling

    Myxedema is a severe form of hypothyroidism, where the thyroid gland does not produce enough thyroid hormones. This condition can lead to symptoms such as extreme fatigue, weight gain, cold intolerance, and swelling of the skin and tissues, particularly noticeable in the face and lower legs. In extreme cases, it can progress to myxedema coma, a life-threatening emergency requiring immediate medical attention.

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    Research 30 of 136

    1. SAT-LB82 Myxedema as Presenting Feature of Profound Primary Hypothyroidism in a Toddler Journal of the Endocrine Society · 2020
    2. SUN-585 A Case of Atypical Myxedema in Hypothyroidism Journal of the Endocrine Society · 2019
    3. 12361 An Unusual Case of Myxedema Coma Journal of the Endocrine Society · 2024
    4. Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis Case Reports in Veterinary Medicine · 2021
    5. Hoffman syndrome with the classic sign of myoedema and an unusual finding of systolic heart failure BMJ Case Reports · 2023
    6. Lichen myxedematosus in a patient with hepatocellular carcinoma British Journal of Dermatology · 2000 · 16 citations
    7. Pretibial Myxedema with Graves' Disease: A Case Report and Review of Japanese Literature The Journal of Dermatology · 1998 · 12 citations
    8. Localized alopecic myxedema of the scalp Dermatology online journal · 2023
    9. A Case of pretibial myxedema with hyperthyroidism Linchuang pifuke zazhi · 2000
    10. Thyroid hormone action on skin Dermato-endocrinology · 2011 · 44 citations
    11. Thyroid hormone action on skin. PubMed · 2011 · 24 citations
    12. Dermatologic manifestations of endocrine disorders Current Opinion in Pediatrics · 2012 · 11 citations
    13. Queen Anne sign Canadian Medical Association Journal · 2022 · 3 citations
    14. Hypothyroidism in Dogs 2013 · 3 citations
    15. Incidence, complications and therapeutic evaluation of clinical hypothyroidism in different breeds of dogs BMC Veterinary Research · 2025 · 1 citations
    16. Pathologies of the skin and its appendages in endocrine diseases Dermatology Review · 2016
    17. Editor's Mailbox Postgraduate Medicine · 1997
    18. Cutaneous Manifestations in Thyroid Disorders 2017
    19. Skin manifestations of endocrine diseases Türk Patoloji Dergisi · 2015 · 4 citations
    20. 1249 Critical Care Medicine · 2012
    21. Clinical dermatoendocrinology: saving lives by looking at the skin. PubMed · 2026
    22. Treatment of scleromyxoedema with hydroxychloroquine Journal der Deutschen Dermatologischen Gesellschaft · 2003 · 10 citations
    23. Pediculosis International Journal of Dermatology · 1980 · 2 citations
    24. Colchicine Therapy for Psoriasis Archives of Dermatology · 1976 · 1 citations
    25. “Osler’s phenomenon”: misdiagnosing Cushing’s syndrome Postgraduate Medical Journal · 2003 · 11 citations
    26. Dermatologic manifestations of endocrine disorders Translational pediatrics · 2017 · 86 citations
    27. Exploring the “Thyroid–Skin Connection”: Concepts, Questions, and Clinical Relevance Journal of Investigative Dermatology · 2009 · 49 citations
    28. Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action Dermatology · 2009 · 37 citations
    29. Dermal Mucinosis in the Eosinophilia-Myalgia Syndrome Archives of Dermatology · 1990 · 8 citations
    30. Skin Manifestations of Hypothyroidism-A Clinical Study IOSR Journal of Dental and Medical Sciences · 2013 · 6 citations