April 2020 in “Journal of the Endocrine Society” This case report describes a rare and atypical presentation of primary hypothyroidism with myxedema in a two-year-old boy, highlighting the importance of recognizing unusual symptoms for timely treatment.
April 2019 in “Journal of the Endocrine Society” This case report describes an unusual instance of myxedema in a woman with severe hypothyroidism, presenting with skin findings in atypical locations and improvement following levothyroxine treatment.
October 2024 in “Journal of the Endocrine Society” This case report highlights that in severe illnesses like sepsis, myxedema coma can occur with less elevated TSH levels than typical for primary hypothyroidism, likely due to inflammatory cytokines affecting TSH secretion, even when central lesions are absent.
October 2021 in “Case Reports in Veterinary Medicine” This veterinary case study of a dog with myxedema coma found clinical and pathologic changes including severe thyroid atrophy and marked atherosclerosis consistent with the diagnosis.
October 2023 in “BMJ Case Reports” This case report describes a man diagnosed with Hoffman syndrome, characterized by muscle hypertrophy and weakness due to severe hypothyroidism, who had an excellent response to thyroid hormone replacement.
16 citations
,
August 2000 in “British Journal of Dermatology” In this case report, lichen myxedematosus associated with hepatocellular carcinoma showed progressive improvement in skin lesions without further treatment following tumor resection.
12 citations
,
April 1998 in “The Journal of Dermatology” This report describes a case of pretibial myxedema in an 18-year-old Japanese woman with Graves' disease, along with a review of 112 similar cases from the Japanese literature.
June 2023 in “Dermatology online journal” In this case report, localized myxedema of the scalp was identified in a patient with Graves disease and Hashimoto thyroiditis, emphasizing the varied skin manifestations in autoimmune thyroid conditions.
January 2000 in “Linchuang pifuke zazhi” This case report describes a 58-year-old man with pretibial myxedema and hyperthyroidism, highlighting his cardiac symptoms, exophthalmos, weight loss, and specific dermatological findings over the last four years.
44 citations
,
July 2011 in “Dermato-endocrinology” This article reviews the skin condition myxedema associated with hypothyroidism, highlighting its characteristic non-pitting, glycosaminoglycan-rich nature, and reports no new results.
24 citations
,
July 2011 in “PubMed” This review discusses the classic skin characteristics of hypothyroidism, notably generalized myxedema caused by increased glycosaminoglycan deposition, and reports no clinical results.
11 citations
,
July 2012 in “Current Opinion in Pediatrics” This review discusses dermatologic signs in childhood endocrine disorders and highlights their importance in early diagnosis and treatment, but it reports no new clinical findings.
3 citations
,
February 2022 in “Canadian Medical Association Journal” This case report describes a 72-year-old man who developed symptoms of fatigue and cold intolerance after discontinuing his levothyroxine treatment for hypothyroidism six months earlier.
3 citations
,
January 2013 This chapter discusses hypothyroidism in dogs, highlighting that most cases are due to primary thyroid gland issues and that some breeds may have a hereditary predisposition; it reports no new clinical findings.
1 citations
,
May 2025 in “BMC Veterinary Research” This research highlights the importance of considering hypothyroidism in dogs for early diagnosis and treatment to prevent potentially life-threatening complications, given its relative commonality compared to other diseases causing dermatological changes or obesity in these animals.
January 2016 in “Dermatology Review” This review details various skin manifestations linked to different endocrine disorders but does not report any new clinical results.
November 1997 in “Postgraduate Medicine” Robert T. Leonard Jr. disagrees with Max Rubin's negative views on hair loss treatment, advocating for hormonal tests in women and supporting the use of medications and surgery for androgenetic alopecia.
This study found that specific and nonspecific skin changes can serve as important indicators for diagnosing thyroid diseases, even in patients who appear clinically normal.
4 citations
,
January 2015 in “Türk Patoloji Dergisi” This review discusses the skin manifestations of endocrine diseases and reports no new clinical findings, emphasizing the importance of recognizing these signs for early diagnosis.
research 1249
December 2012 in “Critical Care Medicine” This case report describes a rare presentation of myxedema coma in a 46-year-old woman, initially identified by acute pulmonary embolism, which was managed successfully with thyroid hormone and corticosteroid treatment.
This review described how skin inspection plays a critical role in diagnosing serious endocrine disorders by identifying various cutaneous manifestations linked to conditions like insulin resistance, diabetes, and hyper and hypothyroidism, highlighting its significance in early, life-saving detection.
1 citations
,
May 2006 in “Thyroid Research and Practice” In this study, 56% of patients with hypothyroidism had dry, coarse skin, while weight gain and lethargy were also common complaints.
May 2021 in “Journal of the Endocrine Society” This case report describes severe hypothyroidism exacerbated by nephrotic syndrome in a 62-year-old woman, with a diagnosis of membranous nephropathy linked to significant proteinuria.
2 citations
,
August 2014 in “Journal of the American Academy of Dermatology” This case report details a Taiwanese woman with scleredema adultorum and diabetes mellitus experiencing loss of eccrine glands, which led to frequent heat strokes and anhidrosis despite treatment.
10 citations
,
January 2003 in “Journal der Deutschen Dermatologischen Gesellschaft” In this study, hydroxychloroquine treatment in patients with scleromyxoedema led to complete or partial remission of skin symptoms and improved mobility, though it did not affect paraproteinaemia.
10 citations
,
April 1976 in “Archives of Dermatology” This case report describes a 36-year-old woman experiencing telogen effluvium, noting her recent rapid weight loss and injections of chorionic gonadotropin as potential contributing factors.
6 citations
,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This study found that topical application of triiodothyronine (T3) can induce the transition of hair follicles from the telogen to the anagen phase in mice and stimulate hair shaft growth in vitro.
2 citations
,
June 1980 in “International Journal of Dermatology” This article on pediculosis lacks an abstract and does not report new research findings.
1 citations
,
April 1976 in “Archives of Dermatology” Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.
January 2021 in “Acta Scientiae Veterinariae” In this study, researchers observed that administering the minimum dose of levothyroxine to a hypothyroid Dalmatian effectively restored normal skin condition and hormonal levels, suggesting levothyroxine's potential effectiveness in managing skin changes caused by hypothyroidism in dogs.