150 citations
,
October 2012 in “Clinical Endocrinology” In this retrospective cohort study, women with polycystic ovary syndrome showed high incidence and age-specific prevalence rates of type 2 diabetes, myocardial infarction, and angina, particularly in those over 65.
7 citations
,
October 2020 in “Journal of The American Academy of Dermatology” This systematic review and meta-analysis found that hidradenitis suppurativa is associated with an increased risk of major adverse cardiac events, including cerebrovascular accidents and myocardial infarction, although study heterogeneity affects the magnitude of risk.
September 2023 in “Journal of the American Academy of Dermatology” This study found that the incidence of major adverse cardiovascular events in patients with psoriasis, psoriatic arthritis, and axial spondyloarthritis who received Ixekizumab was low and stable over 3 to 5 years across 25 clinical trials.
278 citations
,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This article reviews the updated ESHRE/ASRM criteria for diagnosing polycystic ovary syndrome, emphasizing the need for continued research and collaboration, but reports no new clinical results.
6 citations
,
January 2021 in “Journal of The American Academy of Dermatology” This letter discusses adverse events related to low-dose oral minoxidil for alopecia, highlighting age-related risks and stressing the importance of contraindication awareness with no new clinical results presented.
January 2024 in “Pharmacoepidemiology” This study found that patients with rheumatoid arthritis taking tofacitinib had higher rates of serious adverse events compared to those with alopecia areata, highlighting the need for careful assessment when using it off-label for alopecia areata.
January 2024 in “International Journal of Health Science” This literature review of hormonal implants in Brazil highlights their expanding usage beyond contraceptive and hormone replacement purposes, noting aesthetic desires like muscle mass gain. However, significant side effects such as cardiovascular events and psychological complications are frequently reported, potentially outweighing the benefits.
November 2009 in “Cambridge University Press eBooks” This article notes that hair restoration surgery generally has a complication rate of less than 1%, but highlights rare instances of serious cardiovascular events.
October 2022 in “European heart journal” In this study, stress levels measured through hair cortisol concentration gradually increased in the days before an acute myocardial infarction, peaking 15 days before the episode in male patients.
April 2026 in “Quality in Sport” This review discusses the cardiovascular risks and events associated with anabolic-androgenic steroid use, suggesting the need for further research on some effects.
October 2025 in “Journal of the Endocrine Society” This study observed that finasteride, while lowering cholesterol levels, did not decrease the prevalence of clinical cardiovascular events or new ECG abnormalities in men with benign prostatic hyperplasia compared to controls, suggesting a potential disconnect between cholesterol management and cardiovascular risk reduction with this treatment.
1 citations
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January 2019 in “Przegla̧d dermatologiczny” This article reviews the concept of cardiodermatology and its application in clinical practice but does not present new empirical findings.
February 2016 in “PubMed” This review discusses testosterone replacement therapy, highlighting that most studies report no increased myocardial infarction risk when the therapy is properly administered with controlled hormone levels; it calls for careful consideration despite insurance coverage challenges.
5 citations
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December 2021 in “Scientific Reports” In this study, researchers found that in mice, gonadal hormones and biological sex do not affect the expression of SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in the respiratory tract, regardless of disease state.
September 2025 in “Journal of Veterinary Cardiology” This study observed that a 13-month-old cat experienced transient myocardial thickening and congestive heart failure episodes likely due to minoxidil intoxication, coinciding with contact with a family member using the drug, suggesting environmental exposure may trigger cardiac events in pets.
January 2018 in “OPen Access Repositorium der Universität Ulm (OPARU) (Ulm University)” This study found that zebrafish can completely regenerate their ventricular myocardium within four weeks, with Wnt/β-catenin signaling playing a critical role in cardiomyocyte dedifferentiation and proliferation.
3 citations
,
July 2024 in “Journal of Vascular Diseases” This review compiles existing research on ischemia-modified albumin (IMA) as a biomarker for myocardial ischemia, highlighting current gaps in understanding its formation and detection, with no new clinical results reported.
January 2025 in “Journal of Carcinogenesis” This review highlights the potential of anti-inflammatory therapies to reduce major adverse cardiac events in patients with ischemic heart disease, emphasizing that such treatments can be effective even without traditional lipid-lowering strategies.
13 citations
,
November 2016 in “The Journal of urology/The journal of urology” In a population-based study, over 72,000 older men were examined, and dutasteride showed no increased risk of heart failure, myocardial infarction, or stroke compared to finasteride, as reported by the researchers.
January 2009 in “Side effects of drugs annual” This study observed no teratogenic effects of oral decongestants and surprisingly favorable neonatal outcomes in Swedish women who used them during pregnancy.
18 citations
,
July 2015 in “Drug Healthcare and Patient Safety” This review discusses the benefits and cardiovascular risks of androgen deprivation therapy for prostate cancer patients, noting that optimizing cardiovascular risk factors is important when using ADT.
28 citations
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May 1978 in “Archives of dermatology” This case report describes a 41-year-old woman with alopecia mucinosa presenting multiple enlarging facial plaques, indicating a potentially non-benign course despite prior classifications.
15 citations
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January 2000 in “Japanese Heart Journal” This case report discusses a 45-year-old Japanese man who developed myocardial infarction while using 1% topical minoxidil for baldness, highlighting the need for caution in patients with cardiovascular disorders.
December 2016 in “Reactions Weekly” Dutasteride and finasteride have equal safety for treating BPH without increased heart risk.
85 citations
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October 2015 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that NF-κB signaling may connect injury response to regenerative processes in zebrafish hearts, potentially aiding the development of cardiac regenerative therapies in humans.
24 citations
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October 2016 in “Oncotarget” This study found that finasteride was associated with more reproductive adverse effects, including sexual dysfunction in men and fetal harm in women, compared to minoxidil in reported alopecia cases.
25 citations
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July 2024 in “Frontiers in Pharmacology” Gepant medications for migraines show varied safety profiles in this study, with specific adverse events reported across systems like gastrointestinal and skin disorders, highlighting the need for tailored treatment and monitoring.
December 2025 in “International journal of research and scientific innovation” This study observed that Nigerian women with PCOS have significantly higher levels of myocardial biomarkers (MYO, cTnI, CK-MB), indicating potential chronic, subclinical myocardial injury in this population.
November 2015 in “Clin-Alert” Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
May 2020 in “Fertility and Sterility” In this study, nonobese normotensive women with PCOS had higher left ventricular mass index compared to healthy controls, which was linked to inflammation and insulin resistance rather than androgen excess.