January 2025 in “Directory of Open access Books (OAPEN Foundation)” This book reviews the symptoms, diagnosis, and treatments for Polycystic Ovary Syndrome, providing a comprehensive exploration but reports no new clinical results.
This review discusses lifestyle interventions and dietary modifications for managing PCOS symptoms but reports no new clinical results; the authors emphasize the importance of early diagnosis and management to prevent associated health issues.
May 2015 in “Evidence Based Women Health Journal (Online)” This study found that myoinositol combined with D-chiroinositol was more effective than metformin in improving weight reduction, spontaneous ovulation, and pregnancy rates in women with polycystic ovary syndrome.
26 citations
,
July 2021 in “International journal of adolescent medicine and health” This review covers various treatments for managing PCOS symptoms and infertility, noting that aromatase inhibitors may be as or more effective than clomiphene citrate for ovulation induction but reports no new clinical results.
This review investigates the relationship between polycystic ovarian syndrome and the development of type 2 diabetes mellitus but reports no new clinical findings.
October 2025 in “Biomolecules” This study found that prolonged intermittent fasting in diet-induced obese mice led to increased levels of inositol monophosphates in white adipose tissue, improved insulin sensitivity, and reduced body weight and fat mass, suggesting a novel metabolic adaptation mechanism.
28 citations
,
October 1987 in “PubMed” This study found that treating Tradescantia stamen hair cells with LiCl disrupts mitotic progression, leading to metaphase arrest, which can be reversed by myo-inositol or CaCl2 addition.
24 citations
,
July 2019 in “Journal of Obstetrics and Gynaecology” This study found that a 12-week supplementation with a combination of insulin sensitizing agents, antioxidants, and vitamins significantly improved menstrual cyclicity, acne, and hirsutism in women with PCOS, with additional weight loss benefits in obese subjects.
March 2026 in “Physical Education Health and Social Sciences” In this randomized controlled trial, combining cinnamon and inositol led to significant improvements in metabolic and hormonal parameters, such as reduced LH, testosterone, fasting glucose, and ovarian ultrasound scores, in overweight women with PCOS, indicating superior benefits over either supplement alone.
18 citations
,
November 2016 in “International clinical psychopharmacology” This study found that in a 10-week trial, inositol did not significantly reduce trichotillomania symptoms compared to placebo, although 42.1% of inositol-treated patients felt 'much or very much improved' at the study's end.
September 2018 in “Cosmetics” This study found that anisotropic osmolyte solutions may improve hair follicle turnover and condition in both in vitro and in silico models, as well as in human volunteers with hair disorders.
44 citations
,
February 2012 in “The journal of neuroscience/The Journal of neuroscience” This study observed that Ptprq mutant mice exhibit significant abnormalities in hair bundle structure and vestibular dysfunction, suggesting similar issues may contribute to hearing loss and vestibular problems in humans with PTPRQ mutations.
25 citations
,
January 1944 in “Experimental Biology and Medicine” This study found that supplementing inositol in a diet containing sulfasuxidine prevents symmetrical alopecia and promotes better growth and appearance in rats.
December 2015 in “Endocrinology and Metabolic Syndrome” This study observed that treatment with inositol, in various doses based on BMI, led to significant reductions in hair loss and symptoms of hyperandrogenism in patients with androgenetic alopecia.
September 2015 in “Journal of Steroids & Hormonal Science” This study reports a significant reduction in hair loss and other androgen-related signs in hyperandrogenism patients using inositol supplementation, although further research is needed to confirm these findings.
54 citations
,
August 2017 in “Gynecological Endocrinology” This review discusses treatments for polycystic ovary syndrome, including lifestyle changes, oral contraceptives, and various medications, and reports no new clinical findings; the authors highlight the potential of statins and inositol for managing symptoms.
August 2024 in “Indian Journal Of Clinical Practice” A balanced diet and healthy lifestyle help manage PCOS symptoms.
9 citations
,
August 2024 in “Australian Prescriber” This review highlights that pharmacotherapy for polycystic ovary syndrome should address individual patient concerns, with metformin beneficial for reducing weight and metabolic risk, and lifestyle modifications also important.
1 citations
,
January 2022 in “Journal of experimental and clinical medicine” This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.
March 2026 in “Anti-Aging Eastern Europe” This review examines current evidence on personalized management strategies for PCOS, but does not present new clinical results; the authors advocate for treatments tailored to predominant symptoms and individual health profiles.
November 2025 in “Fertility Gynecology and Andrology” This study highlights that polycystic ovary syndrome develops through genetic and environmental factors, with insulin resistance as a key mechanism, impacting the risk of metabolic and cardiovascular conditions.
January 2025 in “International Journal for Research Trends and Innovation” This review examines the factors contributing to Polycystic Ovary Syndrome in India, discussing genetic, lifestyle, and environmental influences, but provides no new clinical results.
February 2024 in “Biomedical journal of scientific & technical research” This study explored whether inositol and phytic acid, components from rice bran, could be effective and safe alternatives to minoxidil for promoting hair growth, due to concerns about minoxidil's side effects with long-term use in women. Results are not reported.
February 2024 in “Journal of Education, Health and Sport” This review discusses current pharmacological and non-pharmacological treatment strategies for PCOS, emphasizing the need for a personalized, multimodal approach due to incomplete understanding of the syndrome's pathogenesis.
May 2022 in “Maǧallaẗ Buḥūṯ Al-Tarbiyyaẗ Al-Nawʿiyyaẗ (Print)” In this study, a high inositol diet, with or without supplements, significantly improved androgen levels, insulin sensitivity, and certain metabolic indicators in women with PCOS over three months.
February 2020 in “Diabetologie Und Stoffwechsel” This article reviews treatment strategies for polycystic ovary syndrome, specifically recommending letrozole for infertility, while also discussing lifestyle changes and other potential therapies, and reports no new research findings.
November 2017 in “Elsevier eBooks” This article reviews the complications and health risks associated with polycystic ovary syndrome and reports no new clinical findings.
December 2024 in “African Journal of Biomedical Research” This review discusses various risk factors and potential therapeutic interventions for PCOS but reports no new clinical results.
11 citations
,
October 1941 in “Experimental Biology and Medicine” PABA helps prevent gray hair and hair loss in mice.
44 citations
,
September 2020 in “International Journal of Molecular Sciences” This review discusses the disruption of hormonal and metabolic rhythms in polycystic ovary syndrome and explores potential drug targets to address its molecular causes, without providing new clinical results.