In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.
October 2024 in “Irish Journal of Medical Science (1971 -)” In this study, TENS of the T6 dermatome over a longer term was explored for its effects on weight, blood pressure, heart rate, and appetite-regulating hormones in obese subjects with moderate obstructive sleep apnea; however, results are not reported in the abstract.
September 2024 in “Cermin Dunia Kedokteran” This article reviews Frambusia, a skin-contact-spread tropical infection, and stresses improving medical professionals' diagnostic and treatment skills to achieve the WHO's eradication target by 2030, without reporting new results.
May 2024 in “ABDIKAN Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi” This study identified a high prevalence of Enterobiasis among children in Indonesia, linked to poor sanitation and healthcare access, and found that a holistic family medicine approach improved patient understanding and treatment compliance, thereby enhancing their quality of life.
April 2024 in “Journal of cancer research and clinical oncology” This review discusses the isolation, characterization, and potential clinical applications of tissue-derived extracellular vesicles in cancer diagnosis, prognosis, and treatment, noting their significance but highlighting the risks and need for appropriate protocols.
December 2023 in “Curēus” In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
December 2023 in “Revista de la Facultad de Ciencias Médicas (Quito)” This case report describes a 15-year-old female whose initial systemic lupus erythematosus manifestations were fever and rash appearing separately, illustrating diagnostic challenges between SLE and infection.
October 2023 in “Advancement in yoga and physical therapy” This narrative review explores the potential influence of brown adipose tissue on polycystic ovary syndrome and reports no new experimental findings.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
This case report details a 38-year-old woman in Sri Lanka diagnosed with systemic lupus erythematosus-associated protein-losing enteropathy, identified through hypoalbuminemia and EULAR criteria in a resource-limited setting.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
March 2021 in “Research Square (Research Square)” This study found that patients with RASopathies demonstrated lower levels of serum IgA and CD8 T cells compared to controls, potentially indicating an increased risk of developing autoimmune disorders.
October 2017 in “The American journal of gastroenterology” This case series highlights severe micronutrient deficiencies and complications in three patients who did not adhere to follow-up care after Roux-en-Y gastric bypass, emphasizing the importance of regular nutritional monitoring.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study investigates whether lymphocytes from mice with secondary alopecia areata can effectively induce the disease in a C3H/HeH mouse model, similar to lymphocytes from mice with spontaneous disease.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests a connection between the unfolded protein response and upregulation of NKG2D ligands in stressed hair follicles, highlighting a potential role of PRDX5 in alopecia areata pathogenesis.
July 2016 in “American Journal of Dermatopathology” The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.
December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)” This study showed that regulation of adipose androgen generation via AKR1C3 may contribute to a cycle of hyperinsulinaemia and lipid accumulation in women with PCOS.
January 2015 in “D-Scholarship@Pitt (University of Pittsburgh)” This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
January 2012 in “heiDOK (Heidelberg University)” In this study, researchers observed that dormant TRP-2+ melanoma cells in bone marrow can interact with CD8+ T cells in tumor-bearing ret transgenic mice, potentially influencing immune responses.
July 2011 in “British Journal of Dermatology” Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.
October 1993 in “Proceedings of The Nutrition Society” Dietary choices, especially fat type, can influence health.
January 1981 in “The Journal of Toxicological Sciences” In this study, beagle dogs treated with hydrocortisone 17-butyrate 21-propionate ointment showed various toxic effects, including acne-like skin changes and organ atrophy, which returned to normal after a recovery period.
1 citations
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October 2015 in “OakTrust (Texas A&M University Libraries)” This study found that harp seal vibrissal innervation studies focusing only on lateral vibrissae may overestimate total innervation by about 20%, highlighting the importance of considering the entire snout.
In this study, highly dynamic remodeling was observed in mouse somatosensory axons and Merkel cells, indicating that epithelial-neural interactions help maintain homeostatic remodeling, with additional intrinsic neural mechanisms contributing to axonal plasticity.
February 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in adult mouse skin, somatosensory axon plasticity is highly dynamic and influenced by epithelial-neural crosstalk and intrinsic neural mechanisms.
January 2025 in “Nature Communications” Using synchrotron X-ray imaging, this study mapped the complex innervation of male rat vibrissa follicles, revealing distinct types of myelinated afferent neurons and patterns of axonal organization that may inform sensory processing in the brainstem.
201 citations
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November 1964 in “Journal of neurophysiology” The cuneate nucleus has two main neuron types: relay neurons and interneurons.
181 citations
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December 2017 in “Trends in immunology” This review discusses the roles and interactions of intestinal intraepithelial lymphocytes in maintaining mucosal barrier integrity and highlights how their dysregulated responses may contribute to intestinal pathologies.
227 citations
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February 1989 in “The Journal of Comparative Neurology” This study found that calcitonin‐gene‐related peptide immunoreactive sensory axons in rats are predominantly involved in tissue maintenance rather than nociceptive functions.