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The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

New therapies are being developed that target integrin pathways to treat various diseases.

TLR4 is important in aging-related diseases and could be a new treatment target.

Zebrafish are useful for studying and developing treatments for human skin diseases.

Cannabinoids may help treat various skin conditions.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Tadalafil and Finasteride may help treat aggressive melanoma.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.