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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

New drugs and combination therapies are improving treatment for lower urinary tract symptoms.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Low-level laser therapy seems to help dogs with noninflammatory alopecia grow hair back.

Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.

Ringworm around the eyes often gets misdiagnosed, leading to eyelash loss, but antifungal treatment can improve the condition.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

Hair restoration surgery can potentially treat primary scarring alopecias, but it's important to start early medication, ensure patient remission before transplant, and monitor after surgery.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Applying an extract from Perilla frutescens helps hair grow and fights the effects of hair loss hormones.

Dosing time affects finasteride's effectiveness and safety in rats.

Topical oxygen therapy may improve treatments for hair loss, acne, and chronic skin diseases with minimal side effects.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

BeauTop improves hair growth in androgenetic alopecia patients.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Timosaponin BII, a plant extract, was found to promote hair growth in mice, similarly to minoxidil.

Dutasteride reduces hospitalization and prostate cancer risk compared to finasteride, potentially offsetting its higher cost.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Hormone therapy for breast cancer often leads to sexual issues like vaginal dryness and decreased libido.

People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.

A lotion with Centella asiatica extract reduced hair loss by 41% and increased hair strength without side effects.

Finasteride before TURP reduces blood loss and improves early postoperative quality of life.