research Development and Homeostasis of the Sebaceous Gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
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research Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT Signaling Axis
PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
research Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla
All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
research Circadian Clocks: From Stem Cells to Tissue Homeostasis and Regeneration
Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation
Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
research A Review on Jasmonic Acid and Its Derivatives
Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
research Wnt Signaling in Skin Organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
research Regeneration of Skin Appendages and Nerves: Current Status and Further Challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells
Androgens slow hair growth by altering Wnt signaling in balding cells.
research Next Generation Human Skin Constructs as Advanced Tools for Drug Development
Advanced human skin models improve drug development and could replace animal testing.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research From Neural Crest Cells to Melanocytes: Cellular Plasticity During Development and Beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Proinflammatory Cytokines Regulate Epidermal Stem Cells in Wound Epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?
Low iron and vitamin D levels are linked to hair loss in women.
research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert
A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.
research The Control of Hair Growth: An Overview
Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
research Apoptosis and Cutaneous Biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Role of S-Palmitoylation by ZDHHC13 in Mitochondrial Function and Metabolism in Liver
ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
research TGFβ and Cancer Metastasis: An Inflammation Link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Exogenous IGF-1 Promotes Hair Growth by Stimulating Cell Proliferation and Downregulating TGF-β1 in C57BL/6 Mice In Vivo
IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
research Spontaneous Tumor Regression in Keratoacanthomas Is Driven by Wnt/Retinoic Acid Signaling Cross-Talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Pitx2, A β-Catenin-Regulated Transcription Factor, Regulates The Differentiation Of Outer Root Sheath Cells Cultured In Vitro
Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.