research Somatic Stem Cell Heterogeneity: Diversity in the Blood, Skin, and Intestinal Stem Cell Compartments
Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
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research MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling
MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
research Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research TNF Superfamily in Skin Appendage Development
TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
research Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence
The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma
WNT10A helps esophageal cancer cells spread and keep renewing themselves.
research Roles of Tumor Suppressors in Regulating Tumor-Associated Inflammation
Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research Aromatase Deficiency in a Male Patient: Case Report and Literature Review
A male with aromatase deficiency improved bone health with estradiol treatment.
research Fate of Prominin-1 Expressing Dermal Papilla Cells During Homeostasis, Wound Healing, and Wnt Activation
Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
research Responses of Hair Follicle–Associated Structures to Loss of Planar Cell Polarity Signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research Smad4-Dependent Desmoglein-4 Expression Contributes to Hair Follicle Integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Hedgehog And Gli Signaling In Embryonic Mammary Gland Development
Hedgehog signaling is crucial for mammary gland development over hair follicles.
research ILK Modulates Epithelial Polarity and Matrix Formation in Hair Follicles
ILK is essential for proper hair follicle development and structure.
research Basal Cell Carcinoma, Hedgehog Signaling, and Targeted Therapeutics: The Long and Winding Road
New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.
research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocyte Differentiation in Hair Follicle
A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Preparing the Hair Follicle Canal for Hair Shaft Emergence
A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
research Feather on the Cap of Medicine
Feathers are useful for researching growth, regeneration, and the effects of treatments like chemotherapy on hair loss.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Lrig1-Expressing Epidermal Progenitors Require SCD1 to Maintain the Dermal Papilla Niche
Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
research Sertolioma in a Canadian Husky: Relationship Between Tumor, Hormones, Neurons, and Skin
Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.
research DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells
Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
research Critical Appraisal of Reports on the Treatment of Perioral Dermatitis
Most studies on perioral dermatitis treatment are of low quality, with some agreement on oral tetracycline effectiveness and stopping steroids and cosmetics.
research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research Mechanisms Regulating Skin Immunity and Inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.