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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

BAF200 is essential for proper heart and coronary artery formation.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Rac1 is essential for proper hair structure and color.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

New treatments targeting specific genes show promise for treating keratin disorders.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Prolactin affects when mice shed and grow hair.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Prolactin affects when mice shed and grow hair.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

Lack of cystatin M/E causes thin hair and dry skin.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.