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Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

BMP signaling is crucial for skin and hair growth.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Dlx3 is essential for hair growth and regeneration.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Mutations in the RBPJ gene cause Adams-Oliver Syndrome.

The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.

SkQ1 antioxidant improved health and lifespan in mice.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Researchers found genes for cysteine-rich proteins that form the protective layer of hair in humans and sheep.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Vitamin D and its receptor may help prevent skin cancer.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.